[Androstenedione].

Abstract

Test Indications: Diagnosis and differential diagnosis of hyper-androgenism (in conjuction with measurements of other sex-steroids). An initial workup in adults might also include total and bioavailable testosterone measurements. Depending on results, this may be supplemented with measurements of sex hormone-binding globulin and other androgenic steroids (eg, DHEA-S). Diagnosis of congenital adrenal hyperplasia (CAH), in conjunction with measurement of other androgenic precursors, particularly, 17-alphahydroxyprogesterone, 17-alpha-hydroxypregnenolone, DHEA-S and cortisol. Monitoring CAH treatment, in conjunction with testosterone, 17Hydroxyprogesterone, Serum, DHEA-S and DHEA. Diagnosis of premature adrenarche, in conjunction with gonadotropins (FSH, LH) and other adrenal gonadal sex-steroids and their precursors (testosterone total and bioavailable, testosterone total and free, Estradiol, DHEAS, DHEA, Sex hormone binding globulin, 17Hydroxyprogesterone).