{"title":"ANTIBACTERIAL MICROCINES, CLASS II (LITERATURE REVIEW)","authors":"A. Mironov","doi":"10.17816/eid321851","DOIUrl":null,"url":null,"abstract":"The issue of the use in medicine of effective antibacterial substances active against drug-resistant microorganisms remains relevant. Most publications on microcins show undoubted prospects for the further development of these numerous pharmacological agents of bacterial origin with multidirectional action (antibacterial, antiviral, antitumor, etc.). One of the features of the properties of microcins is their specific inhibitory activity against gram-negative microorganisms (first of all, Escherichia, as well as proteus, salmonella, pseudomonas, etc.). This review is compiled with the aim of briefly summarizing current information about one of the groups of microcins (class II) to assess their possible use in practical medicine and in scientific research. The review uses links from the RSCI, Web of Science, Scopus, PubMed databases.","PeriodicalId":93465,"journal":{"name":"Journal of infectious diseases and epidemiology","volume":"47 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of infectious diseases and epidemiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17816/eid321851","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The issue of the use in medicine of effective antibacterial substances active against drug-resistant microorganisms remains relevant. Most publications on microcins show undoubted prospects for the further development of these numerous pharmacological agents of bacterial origin with multidirectional action (antibacterial, antiviral, antitumor, etc.). One of the features of the properties of microcins is their specific inhibitory activity against gram-negative microorganisms (first of all, Escherichia, as well as proteus, salmonella, pseudomonas, etc.). This review is compiled with the aim of briefly summarizing current information about one of the groups of microcins (class II) to assess their possible use in practical medicine and in scientific research. The review uses links from the RSCI, Web of Science, Scopus, PubMed databases.
在医学中使用对耐药微生物有效的抗菌物质的问题仍然是相关的。大多数关于微霉素的出版物显示,这些细菌来源的具有多向作用(抗菌、抗病毒、抗肿瘤等)的众多药理学药物无疑具有进一步发展的前景。微霉素的特性之一是其对革兰氏阴性微生物(首先是埃希氏菌,以及变形杆菌、沙门氏菌、假单胞菌等)的特异性抑制活性。编写这篇综述的目的是简要总结目前关于一类微霉素(II类)的信息,以评估它们在实际医学和科学研究中的可能应用。这篇综述使用了来自RSCI、Web of Science、Scopus、PubMed等数据库的链接。