A Short Review on Organ-on-a-chip Technology

Abstract

Organ-on-a-chip (OOAC), also known as microphysiological systems or 'tissue chips' (the names are interchangeable), have gained a lot of attention in recent years because of their ability to provide information at different phases of the drug development process. This cutting-edge technology could help researchers better understand normal human organ function and disease pathology, as well as forecast the safety and efficacy of experimental medications in humans. As a result, they are expected to be beneficial supplements to standard preclinical cell culture methods and in vivo animal research in the near future, and possibly even replacements in the long run. This article presents an overview of this rapidly expanding technology.