A Snapshot of Different Types of Under Research Vaccines Against COVID-9: A Review

Milad Zandi, S. Rashid, Sepideh Nasimzadeh, Behzad Pourhossein, M. Fazeli
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引用次数: 4

Abstract

SARS-CoV-2 as an emerging coronavirus, which first emerged in late 2019 in China causes a respiratory disease called “Coronavirus Disease 2019 (COVID-19)’’. SARS-CoV-2 has since infected more than 26 million people worldwide and caused more than 864000 deaths as of September 04, 2020. The SARS-CoV-2 spike (S) protein consists of two subunits: S1 and S2, which plays a role in binding to cellular receptors and mediating the fusion process between the membranes of the virus and host cells. The S protein has an important role to induce neutralizing-antibody, as well as protective immunity, during SARS-CoV-2 infection. In this review, we focused on different types of the vaccine against COVID-19. *Corresponding Author: Maryam Fazeli; Email: m.fazeli@umsha.ac.ir Please cite this article as: Zandi M, Rashid S, Nasimzade S, Pourhossein B, Fazel M. A Snapshot of Different Types of Under Research Vaccines Against COVID-9: A Review. Arch Med Lab Sci. 2020;6:e7. https://doi.org/10.22037/amls.v6.32379
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不同类型的正在研究的抗COVID-9疫苗综述
SARS-CoV-2是一种新型冠状病毒,于2019年底在中国首次出现,引发了一种名为“2019冠状病毒病(COVID-19)”的呼吸道疾病。截至2020年9月4日,SARS-CoV-2已在全球感染了2600多万人,造成86.4万多人死亡。SARS-CoV-2刺突(S)蛋白由S1和S2两个亚基组成,其作用是与细胞受体结合并介导病毒膜与宿主细胞之间的融合过程。在SARS-CoV-2感染过程中,S蛋白在诱导中和抗体和保护性免疫中发挥重要作用。在这篇综述中,我们重点介绍了不同类型的COVID-19疫苗。*通讯作者:Maryam Fazeli;Zandi M, Rashid S, Nasimzade S, Pourhossein B, Fazel M.不同类型的正在研究的抗COVID-9疫苗综述中华医学杂志,2020;6:7。https://doi.org/10.22037/amls.v6.32379
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