Toxicological Analysis of Drugs in Human Mummified Bodies and Proposed Guidelines.

Angela Silva-Bessa, Shari L Forbes, Maria Teresa Ferreira, Ricardo Jorge Dinis-Oliveira
{"title":"Toxicological Analysis of Drugs in Human Mummified Bodies and Proposed Guidelines.","authors":"Angela Silva-Bessa,&nbsp;Shari L Forbes,&nbsp;Maria Teresa Ferreira,&nbsp;Ricardo Jorge Dinis-Oliveira","doi":"10.2174/2589977514666220914084543","DOIUrl":null,"url":null,"abstract":"<p><p>From palaeopathology to forensic taphonomy, mummified human bodies constitute biological archives of paramount importance. Toxicology analysis of endobiotics and xenobiotics has already shown value to archaeological mummies research with detecting heavy metals, sedative-hypnotic drugs, and stimulants. Thanks to the large window of drug detection in hair and nails, the information from such studies has increased the scientific community's knowledge regarding past populations' lifestyles. Still, few bibliographic references exist regarding toxicology reports in mummified bodies from forensic settings. Here, the authors aim to draw attention to the valuable contribution of toxicology analysis, taking into account previously conducted studies and their findings. Given that sample collection on mummified bodies from forensic scenarios may not always happen in laboratories or autopsy rooms, the authors also suggest guidelines for in situ sampling of forensic mummies. It is expected that the present technical note will encourage experts to perform toxicology analysis in mummified bodies and publish their case reports more often.</p>","PeriodicalId":37008,"journal":{"name":"Current Drug Research Reviews","volume":"15 1","pages":"62-72"},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Drug Research Reviews","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/2589977514666220914084543","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 2

Abstract

From palaeopathology to forensic taphonomy, mummified human bodies constitute biological archives of paramount importance. Toxicology analysis of endobiotics and xenobiotics has already shown value to archaeological mummies research with detecting heavy metals, sedative-hypnotic drugs, and stimulants. Thanks to the large window of drug detection in hair and nails, the information from such studies has increased the scientific community's knowledge regarding past populations' lifestyles. Still, few bibliographic references exist regarding toxicology reports in mummified bodies from forensic settings. Here, the authors aim to draw attention to the valuable contribution of toxicology analysis, taking into account previously conducted studies and their findings. Given that sample collection on mummified bodies from forensic scenarios may not always happen in laboratories or autopsy rooms, the authors also suggest guidelines for in situ sampling of forensic mummies. It is expected that the present technical note will encourage experts to perform toxicology analysis in mummified bodies and publish their case reports more often.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
人体干尸中药物的毒理学分析及建议指南。
从古病理学到法医埋藏学,木乃伊人体构成了极为重要的生物档案。内源性药物和外源性药物的毒理学分析已经在考古木乃伊研究中显示出检测重金属、镇静催眠药物和兴奋剂的价值。由于在头发和指甲中有很大的药物检测窗口,从这些研究中获得的信息增加了科学界对过去人口生活方式的了解。尽管如此,很少有参考书目存在关于法医设置木乃伊尸体的毒理学报告。在这里,作者的目的是提请注意毒理学分析的宝贵贡献,考虑到以前进行的研究和他们的发现。鉴于从法医场景中收集木乃伊尸体的样本可能并不总是在实验室或尸检室进行,作者还建议了法医木乃伊现场采样的指导方针。预期本技术说明将鼓励专家对木乃伊尸体进行毒理学分析,并更经常地发表他们的病例报告。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Current Drug Research Reviews
Current Drug Research Reviews Medicine-Psychiatry and Mental Health
CiteScore
3.70
自引率
0.00%
发文量
38
期刊最新文献
Advances in Human Brain Organoids: Methodological Innovations and Future Directions for Drug Discovery. Advancing Green Chemistry in Antiviral Therapeutics: A Comprehensive Review. Arbutin's Potential in Neuroprotection: A Promising Role in Mitigating Neurodegenerative Diseases. Ralstonia mannitolilytica Infections: A Systematic Review of Case Reports Unveiling Clinical Patterns and Therapeutic Insights. Synergistic Outcomes in Drug Delivery: Exploring Harmonious Architectures of Interpenetrating Polymer Networks.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1