A Review on Aptamer-Conjugated Quantum Dot Nanosystems for Cancer Imaging and Theranostic

Elmira Samimi, P. Karami, Mohammad Johari Ahar
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引用次数: 7

Abstract

Over the last 10 years, fluorescent semiconductor QD (quantum dot)-aptamer conjugates have emerged as an efficient platform for cancer imaging and therapy in animal models and in vitro. In addition, these conjugates show potential in a wide range of applications in environmental monitoring, disease diagnosis, and bio-sensing. The present review represents the recent developments in QDaptamer bio-conjugates for applications in cancer studies. It starts with a brief introduction to Semiconductor Quantum dots (QDs), bio-conjugation of QDs and aptamer molecules, and advantages-disadvantages of using these novel tools for biochemical applications.
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适体共轭量子点纳米系统在肿瘤成像和治疗中的研究进展
在过去的10年里,荧光半导体量子点适体偶联物已经成为动物模型和体外癌症成像和治疗的有效平台。此外,这些偶联物在环境监测、疾病诊断和生物传感方面具有广泛的应用潜力。本文综述了QDaptamer生物偶联物在癌症研究中的最新进展。本文首先简要介绍了半导体量子点(QDs),量子点与适配体分子的生物偶联,以及将这些新工具用于生化应用的优缺点。
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