In Vitro Release of a Tumor‐Antigen (TA‐4) by Human Cervical Squamous Cell Carcinoma

S. Aramaki, H. Kato, H. Morioka, H. Toyoshima, T. Torigoe
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Abstract

The release of a human squamous cell carcinoma antigen (TA-4) was studied by in vitro incubation of squamous cell carcinoma tissues and normal squamous epithelium of the uterine cervix. TA-4 activity was determined by a radioimmunoassay method using a monospecific antiserum to TA-4. TA-4 activity was found in both malignant and non-malignant tissues. However, the malignant tissue released significantly larger amounts of TA-4 than the non-malignant tissue during 72 hours incubation.
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肿瘤抗原(TA - 4)在人宫颈鳞状细胞癌中的体外释放
通过体外培养人宫颈鳞癌组织和正常宫颈鳞上皮,研究了人鳞癌抗原(TA-4)的释放。用TA-4单特异性抗血清放射免疫法测定TA-4活性。TA-4活性在恶性和非恶性组织中均有发现。然而,在72小时的孵育过程中,恶性组织释放的TA-4明显多于非恶性组织。
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