Study of phenol carboxylic acids in echinacea grass and echinacea tablets in order to develop a technique for their quantitative determination using high-performance liquid chromatography (HPLC)

Anastasia Yuryevna Romarchuk
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Abstract

Echinacea herb and preparations based on it have the immunomodulatory and anti-inflammatory properties necessary for today, which is due to the presence of phenolcarboxylic acids in their composition. At the moment, the quantitative determination of phenolcarboxylic acids in echinacea tablets requires time-consuming sample preparation and determination by a spectrophotometric method that does not have sufficient specificity. In this regard, it is proposed to standardize the quantitative determination of phenolcarboxylic acids in echinacea tablets by HPLC, which will effectively separate the components of the mixture to study its composition, establish the dominant of chicory acid in the water-ethanol extract, and also reduce the time spent on analysis.
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紫锥菊草和紫锥菊片中酚羧酸含量的高效液相色谱法研究
紫锥菊草本植物及其制剂具有今天必需的免疫调节和抗炎特性,这是由于其成分中酚羧酸的存在。目前,紫锥菊片中酚羧酸的定量测定需要耗时制样和分光光度法测定,且特异性不足。为此,建议采用高效液相色谱法规范紫锥菊片中酚羧酸的定量测定,既能有效分离混合物的成分,研究其成分,又能确立水乙醇提取物中菊苣酸的优势含量,减少分析时间。
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