The Value of Platelet Indices and platelet to lymphocyte ratio as predictors of severity of Preeclampsia in Iraqi women

Abstract

  To assess the significance of platelet indices and the ratio of platelet to lymphocyte as an early prediction of patients with severity of Preeclampsia. Ninety women were enrolled in three groups: group I: (In=30) women diagnosed as non-severe preeclampsia, group II: (n=30) women diagnosed as severe preeclampsia, and group: III (n=30) age-matched normal pregnant women as a control group. The platelet parameters namely: platelet count (PC), mean platelet volume (MPV), platelet distribution width (PDW), and platelet to lymphocyte ratio (P/L ratio) were evaluated and compared among the study groups.Our findings showed a significant difference among the studied groups regarding the followings: body mass index BMI, systolic blood pressure (SBP) and diastolic blood pressure (DBP) at P-value < 0.05. Mean Platelet Volume and Platelet Distribution Width showed no significant differences between the study groups (P= 0.693 and 0.118, respectively). In all groups, highly decrease in platelet count (p = 0.01) and platelet to lymphocyte ratio (p= 0.024) were found. The changes in the platelet indices are more evident in mothers with severe preeclampsia especially the ratio between platelet and lymphocyte. Thus, Platelet indices could be used as biomarkers for early prediction of preeclampsia seriousness.