A review on pulmonary and mediastinal synovial sarcoma.

Q3 Pharmacology, Toxicology and Pharmaceutics Journal of Basic and Clinical Physiology and Pharmacology Pub Date : 2023-03-01 DOI:10.1515/jbcpp-2022-0286
Kristin Purnama Dewi, Ivana Purnama Dewi, Iswanto Iswanto, Laksmi Wulandari
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Abstract

Sarcoma is defined as a tumor located in the thoracic cavity. However, sarcoma can occur on every side of the body. Synovial sarcoma is a rare soft tissue tumor originating from pluripotent with a high malignancy rate. The most common predilection of synovial sarcoma is in the joints. Primary synovial sarcoma of the lung and mediastinum are rare tumors and generally malignant. There are only a few cases have been reported. Definite diagnosis is made by histopathological, immunohistochemistry, and cytogenetic examination. The management strategy for synovial sarcoma requires multimodality treatment with surgery, chemotherapy, and radiotherapy. However, effective and relatively non-toxic therapy for primary synovial sarcoma is still developed. The five years life expectancy is higher if the patient received adjuvant radiotherapy and/or chemotherapy after surgery.

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肺和纵隔滑膜肉瘤的研究进展。
肉瘤被定义为位于胸腔的肿瘤。然而,肉瘤可以发生在身体的每一边。滑膜肉瘤是一种罕见的软组织肿瘤,起源于多能性,恶性率高。滑膜肉瘤最常发生于关节。摘要原发性肺和纵隔滑膜肉瘤是一种罕见的恶性肿瘤。据报道只有少数病例。通过组织病理学、免疫组织化学和细胞遗传学检查作出明确诊断。滑膜肉瘤的治疗策略需要多模式治疗,包括手术、化疗和放疗。然而,对原发性滑膜肉瘤有效且相对无毒的治疗方法仍在研究中。如果患者术后接受辅助放疗和/或化疗,5年的预期寿命会更高。
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来源期刊
Journal of Basic and Clinical Physiology and Pharmacology
Journal of Basic and Clinical Physiology and Pharmacology Pharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
3.90
自引率
0.00%
发文量
53
期刊介绍: The Journal of Basic and Clinical Physiology and Pharmacology (JBCPP) is a peer-reviewed bi-monthly published journal in experimental medicine. JBCPP publishes novel research in the physiological and pharmacological sciences, including brain research; cardiovascular-pulmonary interactions; exercise; thermal control; haematology; immune response; inflammation; metabolism; oxidative stress; and phytotherapy. As the borders between physiology, pharmacology and biochemistry become increasingly blurred, we also welcome papers using cutting-edge techniques in cellular and/or molecular biology to link descriptive or behavioral studies with cellular and molecular mechanisms underlying the integrative processes. Topics: Behavior and Neuroprotection, Reproduction, Genotoxicity and Cytotoxicity, Vascular Conditions, Cardiovascular Function, Cardiovascular-Pulmonary Interactions, Oxidative Stress, Metabolism, Immune Response, Hematological Profile, Inflammation, Infection, Phytotherapy.
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