Atypical extra nasopharyngeal angiofibroma in an unusual location: tonsil posterior pillar (oropharynx)

Shweta Mittal, M. Priya, S. Varshney, Sumeet Angral, Joyson Xavier, M. Malhotra, A. Bhardwaj, Amit Kumar, A. Tyagi
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Abstract

Introduction. Angiofibroma is a benign, locally aggressive highly vascular tumor that typically affects young adolescent males and has a pathognomonic epicenter of origin in the nasopharynx. The atypical angiofibromas share the same histological features as that of Juvenile nasopharyngeal angiofibroma, however they differ significantly in their clinical features. Aim. Here we are reporting a very rare case of atypical angiofibroma in an adult male presenting as a non-vascular mass in the oropharynx with posterior pillar as the subsite. Description of the case. A 26-years old male patient presented with chief complaints of foreign body sensation and mass in throat for one and a half months which was gradually progressive in size. Histopathological examination revealed a lesion with an intricate mixture of blood vessels, irregular fibrous stroma with loose edematous and fibrous area along with multinucleated stromal cells which was suggestive of angiofibroma. Conclusion. Oropharyngeal angiofibroma, being an atypical angiofibroma in terms of site and presenting complaints, presents a diagnostic challenge. Though rare, it should always be kept as a differential diagnosis in any oropharyngeal mass irrespective of its vascularity, typical age or sex of the patient.
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异位非典型鼻咽外血管纤维瘤:扁桃体后柱(口咽部)
介绍。血管纤维瘤是一种良性的,局部侵袭性的高度血管性肿瘤,通常影响年轻的青少年男性,其发病中心位于鼻咽部。非典型血管纤维瘤与青少年鼻咽血管纤维瘤具有相同的组织学特征,但其临床特征有显著差异。的目标。我们在此报告一例非常罕见的成人男性非典型血管纤维瘤,表现为口咽部的非血管性肿块,并以后柱为亚位。案件描述。患者男,26岁,主诉为异物感及喉部肿物1个半月,体积逐渐增大。组织病理学检查显示病变内有复杂的血管,不规则的纤维间质,疏松水肿和纤维区,伴有多核间质细胞,提示血管纤维瘤。结论。口咽血管纤维瘤是一种不典型的血管纤维瘤,在部位和主诉方面,提出了诊断的挑战。虽然罕见,但无论其血管分布,患者的典型年龄或性别如何,它都应作为任何口咽肿块的鉴别诊断。
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