The Safety of Oral Rehydration Solution Jelly for Water and Electrolyte Intake in Patients with Dysphagia.

IF 2.3 3区 医学 Q2 HEALTH CARE SCIENCES & SERVICES Therapeutics and Clinical Risk Management Pub Date : 2023-01-01 DOI:10.2147/TCRM.S398281
Kazuharu Nakagawa, Kanako Yoshimi, Akira Yoshizawa, Kota Aritaki, Kohei Yamaguchi, Ayako Nakane, Haruka Tohara
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Abstract

Purpose: Oral rehydration solutions (ORSs) are effective in replacing fluids and electrolytes and are widely used. OS-1 Jelly (Otsuka Pharmaceutical Factory, Tokushima, Japan) is a jelly drink corresponding to code 2-1 of the 2021 Japanese Dysphagia Diet. Although jelly drinks are less likely to be aspirated than liquids, their physical properties vary depending on the product. Therefore, the severity of dysphagia may affect intake status. This study aimed to investigate the association between the intake status of ORS jelly and swallowing function.

Patients and methods: Thirty-six patients with dysphagia who required videoendoscopic swallowing evaluation at our university hospital were enrolled. Videoendoscopic swallowing evaluation was performed, and each participant swallowed 5 mL of OS-1 Jelly or thickened water modified to International Dysphagia Diet Standardization Initiative (IDDSI) level 2 three times. Statistical analysis was performed to determine the difference in the number of swallows, time until the swallowing reflex, position for inducing the swallowing reflex, presence of pharyngeal residue, penetration, or aspiration between ORS jelly and thickened water.

Results: The time until the swallowing reflex was induced and the position of the swallowing reflex triggered were significantly earlier for ORS jelly (p=0.012, p=0.001). The incidence of pharyngeal residue was significantly lower with ORS jelly (p=0.002). The Penetration-Aspiration Scale score was similar for both samples (p=0.062), and no aspiration was observed in either sample.

Conclusion: Patients with dysphagia who can swallow thickened water modified to IDDSI level 2 can consume ORS jelly. ORS jelly, which requires no thickening and can be easily and safely consumed, is effective for water and electrolyte intake in patients with dysphagia.

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口服补液果冻用于吞咽困难患者饮水和电解质摄入的安全性。
目的:口服补液是一种有效的补充体液和电解质的方法,应用广泛。OS-1果冻(日本德岛大冢制药厂)是一种果冻饮料,对应于2021年日本吞咽困难饮食的代码2-1。虽然果冻饮料不像液体那样容易被吸入,但它们的物理特性因产品而异。因此,吞咽困难的严重程度可能影响摄入状态。本研究旨在探讨ORS果冻摄食状态与吞咽功能的关系。患者和方法:选取36例在我院就诊的吞咽困难患者。进行视频内镜下吞咽评估,每位参与者分别吞咽5 mL符合国际吞咽困难饮食标准化倡议(IDDSI) 2级标准的OS-1果冻或增稠水3次。统计学分析ORS果冻与增稠水在吞咽次数、发生吞咽反射的时间、诱导吞咽反射的位置、咽部残留物的存在、渗透或吸入等方面的差异。结果:ORS果冻诱导吞咽反射的时间和触发吞咽反射的位置明显早于对照组(p=0.012, p=0.001)。口服ORS软膏可显著降低咽部残留的发生率(p=0.002)。两种样本的穿透-吸入量表评分相似(p=0.062),两种样本均未观察到吸入。结论:能吞咽IDDSI 2级加厚水的吞咽困难患者可食用ORS果冻。ORS果冻无需增稠,食用方便、安全,对吞咽困难患者的水电解质摄入有效。
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来源期刊
Therapeutics and Clinical Risk Management
Therapeutics and Clinical Risk Management HEALTH CARE SCIENCES & SERVICES-
CiteScore
4.80
自引率
3.60%
发文量
139
审稿时长
16 weeks
期刊介绍: Therapeutics and Clinical Risk Management is an international, peer-reviewed journal of clinical therapeutics and risk management, focusing on concise rapid reporting of clinical studies in all therapeutic areas, outcomes, safety, and programs for the effective, safe, and sustained use of medicines, therapeutic and surgical interventions in all clinical areas. The journal welcomes submissions covering original research, clinical and epidemiological studies, reviews, guidelines, expert opinion and commentary. The journal will consider case reports but only if they make a valuable and original contribution to the literature. As of 18th March 2019, Therapeutics and Clinical Risk Management will no longer consider meta-analyses for publication. The journal does not accept study protocols, animal-based or cell line-based studies.
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