Gerard O’Leary, Mohammad Reza Pazhouhandeh, Michael Chang, David M. Groppe, T. Valiante, N. Verma, R. Genov
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引用次数: 30
Abstract
The advancement of closed-loop neuromodulation for treating neurological disorders demands: (1) analog circuits monitoring the brain activity uninterruptedly even during neurostimulation, (2) energy-efficient high-efficacy processors for responsive, adaptive, personalized neurostimulation, and (3) safe neurostimulation paradigms with rich spatio-temporal stimuli for controlling the brain's complex dynamics. This paper presents an implantable neural interface processor (NURIP) that addresses these requirements — it performs brain state classification for reliable seizure prediction and contingent seizure abortion.