PHARMACEUTICALLY RELEVANT CuNP, PbNP AND LiNP FROM ASPERGILLUS SPECIES

Mirza Farhana Ishaque, Nabila Anwar Patrawala, Dr. D. R. Majumder
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Abstract

The microorganisms showed the unique potential in the production and accumulation of nano metals with different shapes and sizes by „bioleaching‟. The biological system – Aspergillus species a fungus, isolated from soil was capable of synthesizing nanoparticles such as lithium, lead, and copper using LiCl3 (0.025M), Pb(NO3)2 (0.0002M), and CuSO4(0.025M) as a precursor metal salt. The morphology and the size of the synthesized nano metals as per Scanning Electron Microscopy micrograph confirmed the formation of LiNPs with 85 nm – 100 nm size range, CuNPs with 80 nm – 86 nm in range and PbNPs with 70 nm – 95 nm in range and all three were almost spherical in shape. These nano Metals were further characterized by UV Visible Spectrophotometry, Xray differaction analysis, Fourier Transform Infrared analysis, Cyclic Voltammetry. The ability of these nanoparticles in the field of electronics for the use in batteries were also tested. This green synthesis at room temperature was the most ecofriendly way to produce nano metals.
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从曲霉种中提取的药学上相关的CuNP、PbNP和LiNP
微生物通过“生物浸出”在不同形状和大小的纳米金属的生产和积累中显示出独特的潜力。从土壤中分离出来的真菌曲霉能够以LiCl3 (0.025M)、Pb(NO3)2 (0.000m)和CuSO4(0.025M)作为前体金属盐合成锂、铅和铜等纳米颗粒。扫描电镜观察了合成的纳米金属的形貌和尺寸,结果表明:LiNPs的尺寸范围为85 nm ~ 100 nm, CuNPs的尺寸范围为80 nm ~ 86 nm, PbNPs的尺寸范围为70 nm ~ 95 nm,三者的形状均接近球形。采用紫外可见分光光度法、x射线衍射法、傅里叶变换红外光谱法、循环伏安法对纳米金属进行了进一步表征。这些纳米颗粒在电子领域的电池应用能力也进行了测试。这种在室温下的绿色合成是生产纳米金属的最环保的方法。
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