Possible interactions between garlic and conventional drugs: a review

Mital B. Kansara, A. Jani
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引用次数: 6

Abstract

Herbs can affect body function; therefore, when herbs are taken concurrently with drugs, interactions are possible. The interaction between drugs and herbal medicines is a safe concern and these interactions are especially important for drugs with narrow therapeutics index. The probability of herb-drug interaction can be higher than drug interaction, if conventional drug having single chemical entities, whereas most of the herbal medicinal product contain a mixture of pharmacologically active constituents. The herb-drug interaction may involve either an increase or decrease in the amount of drug in blood, either by altering the absorption, distribution, metabolism, and elimination (ADME) of drug and by antagonizing or synergism of the effect of drug or pharmacodynamics interaction may arise. This article we focus on how garlic interacts with conventional drug or it is favourable or not.
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大蒜和传统药物之间可能的相互作用:综述
草药可以影响身体机能;因此,当草药与药物同时服用时,可能会发生相互作用。药物与草药之间的相互作用是一个安全问题,这些相互作用对治疗指标较窄的药物尤其重要。如果传统药物具有单一化学实体,则草药与药物相互作用的可能性可能高于药物相互作用,而大多数草药产品含有药理活性成分的混合物。草药-药物相互作用可能包括血液中药物量的增加或减少,或通过改变药物的吸收、分布、代谢和消除(ADME),或通过药物作用的拮抗或协同作用或药效学相互作用可能出现。本文将重点讨论大蒜与常规药物的相互作用,以及它是否有利。
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