{"title":"Uso della PET e della SPECT in Psichiatria","authors":"Luca De Peri, Antonio Vita","doi":"10.1016/j.quip.2010.10.005","DOIUrl":null,"url":null,"abstract":"<div><p>In the last 35 years, use of the in vivo brain imaging techniques PET (Positron Emission Tomography) and SPECT (Single Photon Emission Computed Tomography) for the study of psychiatric disorders has revealed several biological alterations in patients with schizophrenia. The present article describes these two imaging modalities, in terms of underlying functional principles and application strategies, and provides a synthetic review of the literature regarding their use in schizophrenia and mood disorders. Particular emphasis is placed on the contribution of SPECT and PET findings in elucidating pathophysiology of these disorders and identifying potential biomarkers of brain function that can be used to assess treatment responses.</p></div>","PeriodicalId":101052,"journal":{"name":"Quaderni Italiani di Psichiatria","volume":"29 4","pages":"Pages 158-164"},"PeriodicalIF":0.0000,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.quip.2010.10.005","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Quaderni Italiani di Psichiatria","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0393064510000587","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
In the last 35 years, use of the in vivo brain imaging techniques PET (Positron Emission Tomography) and SPECT (Single Photon Emission Computed Tomography) for the study of psychiatric disorders has revealed several biological alterations in patients with schizophrenia. The present article describes these two imaging modalities, in terms of underlying functional principles and application strategies, and provides a synthetic review of the literature regarding their use in schizophrenia and mood disorders. Particular emphasis is placed on the contribution of SPECT and PET findings in elucidating pathophysiology of these disorders and identifying potential biomarkers of brain function that can be used to assess treatment responses.
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