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Il perché di un addio 为什么说再见
Pub Date : 2012-12-01 DOI: 10.1016/j.quip.2012.10.001
Eugenio Aguglia, Luigi Ferrannini, Claudio Mencacci, Massimo Clerici
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引用次数: 0
La psicoeducazione nella schizofrenia: evidenze di efficacia e peculiarità di intervento su pazienti e familiari 精神分裂症的心理教育:对患者和家庭成员进行干预的有效性和独特性的证据
Pub Date : 2012-12-01 DOI: 10.1016/j.quip.2012.10.003
Mara Scalese, Tiziana Frieri, Paola Rocca

Introduction

Psychoeducation, a non-pharmacological strategy recommended by current guidelines for the treatment of schizophrenia, integrates elements from different psychotherapeutic approaches and promotes improvement of knowledge regarding the disease and coping skills. The aim of this review is to describe the main evidence of efficacy on psychoeducation in schizophrenia on the basis of recent reviews and meta-analyses, and recently published studies on new approaches in the field.

Discussion and conclusions

Psychoeducation can reduce rates of relapse and rehospitalization, improve adherence to treatment and have other positive effects on patients and their families, such as reduction of burden. Single studies have considered culturally sensitive and other new psychoeducational approaches that would be important for therapeutic interventions especially in multiethnic contexts. Future research should therefore focus patients and their families participate in psychoeducational interventions, but also on the minimum effective psychoeducation dose, on those patients with schizophrenia who do not have supporting families willing to partecipate in family psychoeducation, on standardized outcomes and follow-up periods.

心理教育是目前精神分裂症治疗指南推荐的一种非药物策略,它整合了不同心理治疗方法的要素,促进了对疾病和应对技能的了解。本综述的目的是在最近的综述和荟萃分析的基础上,描述精神分裂症心理教育有效性的主要证据,以及最近发表的关于该领域新方法的研究。讨论与结论心理教育可以降低复发率和再住院率,提高治疗依从性,并对患者及其家属产生减轻负担等积极影响。单一研究考虑了文化敏感和其他新的心理教育方法,这些方法对治疗干预非常重要,特别是在多种族背景下。因此,未来的研究应关注患者及其家庭参与心理教育干预,同时也应关注最低有效心理教育剂量,关注那些没有支持家庭愿意参与家庭心理教育的精神分裂症患者,关注标准化结果和随访期。
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引用次数: 0
Integrazione tra cure primarie e salute mentale a Bologna 博洛尼亚初级保健与精神卫生的结合
Pub Date : 2012-12-01 DOI: 10.1016/j.quip.2011.06.007
Antonella Piazza , Marco Menchetti , Stefano Mimmi , Marco Monari , Cecilia Neri , Emanuela Zanacchini , Ilaria Tarricone , Ivonne Donegani , Domenico Berardi

Introduction

Integration between primary care and mental health care is critical for health-care systems. Some years ago, the Emilia-Romagna Region undertook a project (the “Leggieri Project”) aimed at rationalizing pathways to care and improving the quality of treatments for common psychiatric disorders. The aim of this study was to monitor and assess local implementation of the stepped care model outlined by the regional project.

Materials and methods

We examined all new cases referred to Bologna Mental Health Centers (MHCs) from 2007 through 2009 (N = 15,534). Data on patients, referrals and treatments were collected from Department of Mental Health's Adult Psychiatry database. Standardized incidence rates, rates of referrals from general practitioners (GPs), and stepped care levels were investigated. We compared patient characteristics and treatments of cases referred by GPs and all other cases. A similar analysis was carried out for groups defined by stepped care level.

Results

The annual incidence of MHC referral ranged from 64.7 to 65.8 per 10,000 adult inhabitants. On the whole, 52% of the new cases were referred to the MHCs by GPs: this rate increased over time from 48% to 54%. As for stepped care, MHC care was planned for 55% of the patients referred by GPs, 14% were managed with joint GP and MHC care, and 31% of the new cases were back-referred after a psychiatric consultation. The differences between these levels of care narrowed over the three-year period: cases managed with psychiatric consultations or joint GP-MHC care increased, while those managed exclusively by the MHC decreased. Almost 50% of all cases involving non-Italian immigrants were referred by GPs, although this rate was lower than that observed among Italian patients. These trends were evident in each departmental area. Patients referred by GPs were more likely to be elderly women with common psychiatric disorders. Among these, the cases managed in MHCs had the most severe diagnoses and received the most intensive and long-lasting treatments.

Conclusions

Integration of primary care and mental health care is increasing and seems to be appropriate. In accordance with the recommendations of the regional project, integrated care is used above all for patients with common psychiatric disorders. Collaborative care for severe disorders requires further investigation. For these disorders, which often affect young patients and are frequently associated with comorbidity and a high risk of chronicity evolution, early detection and integrated care are crucial goals for the immediate future.

初级保健和精神卫生保健之间的整合对卫生保健系统至关重要。几年前,艾米利亚-罗马涅大区开展了一个项目(" Leggieri项目"),目的是使护理途径合理化,提高普通精神疾病的治疗质量。本研究的目的是监测和评估区域项目概述的阶梯式护理模式在当地的实施情况。材料和方法我们检查了2007年至2009年博洛尼亚精神卫生中心(MHCs)的所有新病例(N = 15,534)。病人、转诊和治疗的数据收集自心理健康部门的成人精神病学数据库。调查了标准化发病率、全科医生转诊率和分级护理水平。我们比较了全科医生转诊的病例和所有其他病例的患者特征和治疗方法。对按分级护理水平定义的组进行了类似的分析。结果MHC转诊的年发病率为64.7 ~ 65.8 / 10000。总的来说,52%的新病例是由全科医生转介给mhc的:随着时间的推移,这一比例从48%上升到54%。至于阶梯式护理,55%的全科医生转诊的患者计划进行MHC护理,14%的患者接受全科医生和MHC联合护理,31%的新病例在精神病学咨询后再次转诊。在三年的时间里,这些护理水平之间的差异缩小了:接受精神病学咨询或GP-MHC联合护理的病例增加了,而完全由MHC管理的病例减少了。所有涉及非意大利移民的病例中,近50%是由全科医生转诊的,尽管这一比例低于意大利患者。这些趋势在每个部门领域都很明显。全科医生推荐的患者更可能是患有常见精神疾病的老年妇女。在这些病例中,由mhc管理的病例诊断最严重,并接受了最密集和最持久的治疗。结论初级保健与精神卫生保健的结合正在增加,而且似乎是适当的。根据区域项目的建议,综合护理首先用于患有常见精神疾病的患者。对严重疾病的合作护理需要进一步的研究。这些疾病通常影响年轻患者,并经常伴有合并症和高风险的慢性演变,因此早期发现和综合护理是近期的关键目标。
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引用次数: 2
Hoarding e disturbo ossessivo-compulsivo (DOC): due entità cliniche distinte in comorbilità o hoarding secondario al DOC? 囤积障碍性强迫症(DOC):与囤积继发性强迫症合并症的实体临床区别? ?
Pub Date : 2012-12-01 DOI: 10.1016/j.quip.2012.05.002
Umberto Albert, Francesca Barbaro, Andrea Aguglia, Giuseppe Maina, Filippo Bogetto

Introduction

Like most human behaviours, saving and collecting possessions can range from totally normal to excessive or pathological. Hoarding, or compulsive hoarding, are the terms used to refer to excessive form of collecting, which is frequent and disabling for both patients and their families. Hoarding can occur in the context of a variety of neurological and psychiatric conditions; nevertheless, in the last twenty years, it has been considered only as a symptom (or dimension) of obsessive-compulsive disorder (OCD). Recent literature data suggest that hoarding could represent an independent disorder. This leads to a complex issue: what relationship exists between hoarding and OCD? The aim of the present study is to identify, through a review of literature data, psychopathological and clinical features to distinguish the different possible conditions when hoarding and OCD coexist.

Materials and methods

We carried out a search on PubMed/MedLine from 1966 to nowadays. We selected both clinical and review studies, written in English.

Results and discussion

There are two conditions when hoarding and OCD coexist: hoarding as a symptom of OCD, epiphenomenon of the other obsessive-compulsive symptoms; or hoarding disorder as an independent clinical entity comorbid with OCD. In this review, we tried to provide handy and practical information useful for clinicians to characterize the presentation of hoarding symptoms. Furthermore, these information should help clinicians to make a differential diagnosis. Despite some clinical evidences about hoarding, there are several questions that remain to be answered; therefore, additional clinical studies are needed with a more homogeneous methodology.

像大多数人类行为一样,储存和收集物品可能是完全正常的,也可能是过度的或病态的。囤积,或强迫性囤积,是用来指过度形式的收集,这是频繁和致残的病人和他们的家人的术语。囤积症可能发生在各种神经和精神疾病的背景下;然而,在过去的二十年里,它一直被认为只是强迫症(OCD)的一个症状(或维度)。最近的文献数据表明,囤积症可能是一种独立的疾病。这导致了一个复杂的问题:囤积和强迫症之间存在什么关系?本研究的目的是通过文献资料的回顾,确定精神病理和临床特征,以区分囤积和强迫症共存时的不同可能情况。材料与方法我们从1966年至今在PubMed/MedLine进行了检索。我们选择了临床研究和回顾性研究,均以英文撰写。结果与讨论囤积与强迫症并存有两种情况:囤积是强迫症的一种症状,是其他强迫症症状的副现象;或将囤积障碍作为一个独立的临床实体与强迫症共病。在这篇综述中,我们试图为临床医生提供方便和实用的信息来描述囤积症状的表现。此外,这些信息应该有助于临床医生做出鉴别诊断。尽管有一些关于囤积的临床证据,但仍有几个问题有待回答;因此,需要采用更均匀的方法进行额外的临床研究。
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引用次数: 1
Aree di sovrapposizione ed elementi di diagnosi differenziale tra autismo e schizofrenia. Sintesi della letteratura 自闭症和精神分裂症之间的重叠区域和鉴别诊断元素。文献综述
Pub Date : 2012-12-01 DOI: 10.1016/j.quip.2012.07.004
Candida C. Luciano, Domenico Berardi

Introduction

Although their boundaries are discussed from many years, autism and schizophrenia are account as two different clinical entities. This paper presents a review of literature to identify, on one hand, the overlap areas and, on the other hand, distinctive and typical elements of the two disorders.

Discussion

If we see the history of term “autism” and his classification into the Diagnostic and Statistical Manual of Mental Disorders, we can notice that the boundaries between the two disorders are initially vague and then increasingly definite. But, in the years, the diagnostic dimensions have broadened and now we talk about an “autism spectrum” and a “schizophrenic spectrum”.

Conclusions

At the extreme limits of two spectrum, many evidence suggests overlap areas in different levels: clinic, pathogenesis, neuroanatomy, neuropsychology and neuroimaging. Despite these evidences, there is a lack of appropriate instruments to make a correct differential diagnosis.

虽然他们的界限已经讨论了很多年,自闭症和精神分裂症被认为是两个不同的临床实体。本文介绍了文献综述,以确定,一方面,重叠的领域,另一方面,两种疾病的独特和典型的元素。如果我们看看“自闭症”这个词的历史,以及他在《精神疾病诊断与统计手册》中的分类,我们可以注意到,这两种疾病之间的界限最初是模糊的,然后越来越明确。但是,近年来,诊断维度已经扩大,现在我们谈论“自闭症谱系”和“精神分裂症谱系”。结论在两谱的极限范围内,临床、发病机制、神经解剖学、神经心理学和神经影像学等不同层面均存在重叠。尽管有这些证据,但缺乏适当的工具来做出正确的鉴别诊断。
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引用次数: 0
Pub Date : 2012-12-01 DOI: 10.1016/j.quip.2012.03.003
Natale Calderaro, Luigi Ferrannini
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引用次数: 0
Differenze di genere nel disturbo ossessivo-compulsivo: uno studio clinico su 415 pazienti 强迫症的性别差异:一项针对415名患者的临床研究
Pub Date : 2012-12-01 DOI: 10.1016/j.quip.2012.03.004
Umberto Albert, Andrea Aguglia, Francesca Barbaro, David De Cori, Giuseppe Maina, Filippo Bogetto

Objectives

Obsessive-compulsive disorder (OCD), as reported by studies in the literature, has a significant clinical heterogeneity; indeed, authors have moved different subtypes based on the main symptom dimensions, course (episodic vs. chronic), age at onset (early vs. late) and comorbidity (bipolar or tic disorder). Finally, gender has been proposed as a possible subtype. The aim of the study is to evaluate gender-related socio-demographic and clinical differences in a large sample of patients.

Materials and methods

Four hundred fifteen patients with a primary diagnosis of OCD were recruited and evaluated by a semistructured interview. Assessment has been completed with the following rating scales: Y-BOCS, HAM-D, HAM-A, Paykel's scale, SCID-II. The sample was split into two subgroups according to gender.

Results

Males, 217 patients (52.3%), showed an earlier age at onset of obsessive-compulsive symptoms and a significant association with bipolar disorder, sexual obsessions and repetitive rituals. Females showed a correlation between the onset of the disorder and the presence of at least one stressful life event. Also, they were associated with minor depression, eating disorders and washer symptoms.

Discussion

Our study, according to literature data, shows OCD to have specific gender-related differences; to our opinion, however, differences do not completely support the hypothesis of subtyping OCD according to gender. Gender differences seem to be related to other elements such as age at onset; this may be more useful in the future for identifying genetic and environmental predisposing factors and therapeutic strategies.

目的:强迫症(OCD),根据文献研究报告,具有显著的临床异质性;事实上,作者根据主要症状维度、病程(发作性与慢性)、发病年龄(早期与晚期)和合并症(双相情感障碍或抽动障碍)移动了不同的亚型。最后,性别被认为是一个可能的亚型。该研究的目的是在大量患者样本中评估与性别相关的社会人口统计学和临床差异。材料与方法采用半结构化访谈法,招募了415名初诊为强迫症的患者,并对其进行了评估。评估采用以下量表完成:Y-BOCS, HAM-D, HAM-A, Paykel量表,SCID-II。样本按性别分为两组。结果男性强迫症患者217例(52.3%),发病年龄较早,与双相情感障碍、性强迫症和重复性仪式有显著相关性。女性表现出障碍的发作与至少一个有压力的生活事件的存在之间的相关性。此外,它们还与轻度抑郁、饮食失调和洗涤症状有关。根据文献数据,我们的研究表明强迫症具有特定的性别差异;然而,在我们看来,这些差异并不能完全支持强迫症按性别分型的假设。性别差异似乎与其他因素有关,如发病年龄;这可能在未来对确定遗传和环境易感因素和治疗策略更有用。
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引用次数: 1
Sommario/Contents Sommario /高兴
Pub Date : 2012-12-01 DOI: 10.1016/S0393-0645(12)00067-9
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引用次数: 0
Cover 封面
Pub Date : 2012-12-01 DOI: 10.1016/S0393-0645(12)00065-5
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引用次数: 0
Perché è importante una federazione europea delle società delle tossicodipendenze? 为什么欧洲毒品协会联合会很重要?
Pub Date : 2012-12-01 DOI: 10.1016/j.quip.2012.10.002
Giuseppe Carrà , Francesco Bartoli , Daniele Carretta , Emanuele Scafato , Massimo Clerici , Karl F. Mann

Introduction

In the European Union, alcohol use and substance use disorders are among the top five causes of morbidity and mortality due to neurological disease, with an impact on general population comparable to that of cardiovascular diseases and cancer. However, despite this situation research in the field of Addiction Medicine is hampered, first of all because of a lack of funds and the influence of the European Commission in steering them. In addition, the lack of stable links between research groups working in this field limits the possibility to share related knowledge and experience and the development of training networks. In the summer of 2010, 23 scientific societies from 16 European countries established the European Federation of Addiction Societies (EUFAS), with the aim to deal with these issues and to facilitate the development of prevention, treatment, research and health policy programs in relation to substance use disorders.

Conclusions

EUFAS’ efforts should contribute to the development of research, training and clinical practice in the field of Addiction Medicine, thanks to the collaboration between professionals working in the field, not only within the European Union but also in collaboration with organizations and institutions outside Europe.

在欧洲联盟,酒精使用和药物使用失调是神经系统疾病引起发病和死亡的五大原因之一,对普通人群的影响与心血管疾病和癌症相当。然而,尽管存在这种情况,成瘾医学领域的研究受到阻碍,首先是因为缺乏资金和欧洲委员会在指导这些研究方面的影响。此外,在这一领域工作的研究小组之间缺乏稳定的联系,限制了分享有关知识和经验以及发展培训网络的可能性。2010年夏天,来自16个欧洲国家的23个科学学会成立了欧洲成瘾协会联合会,目的是处理这些问题,并促进制定与药物使用障碍有关的预防、治疗、研究和保健政策方案。结论:欧洲成瘾医学联合会的努力应有助于成瘾医学领域的研究、培训和临床实践的发展,这要归功于在该领域工作的专业人员之间的合作,不仅在欧盟内部,而且与欧洲以外的组织和机构的合作。
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引用次数: 0
期刊
Quaderni Italiani di Psichiatria
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