Management of Angle Closure Glaucoma in a Myopic Pregnant Woman during the COVID-19 Pandemic – A Case Journey

Shivani Sharma, M. Chakrabarti, T. Sharma
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Abstract

Introduction: We present a case of a young Caucasian myopic patient with secondary ACG and the management during her pregnancy amidst the COVID-19 pandemic. Angle closure glaucoma (ACG) is an uncommon condition in younger myopic individuals. Thus, ACG in pregnancy is not well researched and no definitive guidelines exist for its treatment. Case Report: This 27-year-old female patient had been diagnosed with hypertensive uveitis and referred to the glaucoma clinic where peripheral anterior synechiae (PAS) was noticed on gonioscopy. As she had subacute angle closure glaucoma symptoms, she had been started on topical pilocarpine drops. She remained stable and under our regular follow up (dates). At her review in January 2021, she notified us that she was 27 weeks pregnant. She had continued pilocarpine drops once a day. Pilocarpine is a category C drug (with potential foetal risk though lack of human studies). Pilocarpine was advised to be stopped in the clinic as intra-ocular pressure is known to stabilise during pregnancy. She was further reviewed in the third trimester and had an uneventful delivery with a healthy baby. Her last review was post-pregnancy. She remained asymptomatic and her intra-ocular pressures were stable for the entire duration. Conclusion: Our case was an unusual presentation of subacute angle closure secondary to PAS in a young myopic female. Her management of pregnancy in the COVID-19 pandemic when secondary to the social distancing rules was challenging as the clinic reviews are limited. We successfully managed timely reviews without risking the patient or the baby of any potential side effects to pilocarpine or COVID-19.
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COVID-19大流行期间近视孕妇闭角型青光眼的治疗——一个病例之旅
我们报告了一例年轻的白人近视继发性ACG患者及其在COVID-19大流行期间的处理。闭角型青光眼(ACG)是一种少见的年轻近视患者。因此,妊娠期ACG的研究并不充分,也没有明确的治疗指南。病例报告:这名27岁的女性患者被诊断为高血压性葡萄膜炎,并被转介到青光眼诊所,在角膜镜检查中发现周围前粘连(PAS)。由于她有亚急性闭角型青光眼症状,她已开始局部使用匹罗卡品滴剂。她保持稳定,并在我们的定期随访(日期)。在2021年1月的复查中,她告诉我们她已经怀孕27周了。她每天服用一次匹罗卡品滴剂。匹罗卡品是C类药物(有潜在的胎儿风险,但缺乏人体研究)。临床建议停用匹罗卡品,因为已知眼压在妊娠期间趋于稳定。她在妊娠晚期接受了进一步检查,顺利分娩,生下了一个健康的宝宝。她最后一次检查是在怀孕后。患者无症状,整个过程中眼压稳定。结论:我们的病例是一个罕见的亚急性闭角继发于PAS的年轻女性。在COVID-19大流行期间,她对怀孕的管理是具有挑战性的,因为诊所审查有限。我们成功地及时进行了复查,没有给患者或婴儿带来匹罗卡品或COVID-19的任何潜在副作用的风险。
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