Novità in tema di malattie infiammatorie croniche intestinali

Filomena Pascarella, Massimo Martinelli, Erasmo Miele, Annamaria Staiano
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Abstract

The inflammatory bowel disease (IBD) are chronic-relapsing disorders which include Crohn's disease, ulcerative colitis and indeterminate colitis. These are classified by age of onset, location and evolution (Montreal Classification). IBD are multifactorial disease, their pathogenesis includes external environment, genetics and immune system. Twentyfive percent of IBD have an onset in childhood; most common symptoms are growth failure and mucus bloody diarrhea. Upper and Lower gastrointestinal endoscopy represents the gold standardfor diagnosis of IBD. Most common drugs are aminosalicylates, steroids, immunosuppressive therapy, nutritional therapy and biological therapy.

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慢性肠道炎症的新发现
炎症性肠病(IBD)是一种慢性复发性疾病,包括克罗恩病、溃疡性结肠炎和不确定性结肠炎。这些按发病年龄、发病地点和发病演变进行分类(蒙特利尔分类)。IBD是一种多因素疾病,其发病机制包括外部环境、遗传和免疫系统。25%的IBD发病于儿童期;最常见的症状是生长衰竭和粘液血性腹泻。上下消化道内窥镜检查是诊断IBD的金标准。最常见的药物是氨基水杨酸盐、类固醇、免疫抑制疗法、营养疗法和生物疗法。
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