Synthesis and Characterization of CSNP-SiO₂ nanocomposite by using antibacterial activity

Abstract

Because of its promising biological achievements, the development of nanotechnology, nanoparticle-based products, and their applications has piqued the interest of many researchers. Inorganic nanomaterials, on the other hand, are well known to be effective antimicrobial agents. Metal nanoparticles, such as Silicon dioxide, are particularly important among the various nanoparticles due to their low cost and ease of availability. Chitosan is a biopolymer derived from chitin, a natural polysaccharide that follows cellulose as the second most abundant polysaccharide. The Precipitation Method was used to create a Chitosan Nanoparticle with SiO2 Nanocomposite (CSNP - SiO2 nanocomposite). TGA, XRD, SEM, FT-IR, PSA, UV, and FL were used to characterize the Chitosan Nanoparticle with SiO2 Nanocomposite. The findings showed that bio-nanocomposites have a greater antibacterial effect due to the combined effect of CS and nanoparticles (NPs). Chitosan/SiO2 nanocomposites were tested for antimicrobial activity against gram-positive and gram-negative microorganisms. The goal was to assess their physical, mechanical, and biological properties, as well as their potential for biomedical applications.