Availability, accessibility and use of antivenom for snakebite envenomation in Africa with proposed strategies to overcome the limitations

IF 3.6 Q2 TOXICOLOGY Toxicon: X Pub Date : 2023-06-01 DOI:10.1016/j.toxcx.2023.100152
Mahmood Muazu Dalhat , Julien Potet , Abdulaziz Mohammed , Nafiisah Chotun , Hanna Amanuel Tesfahunei , Abdulrazaq Garba Habib
{"title":"Availability, accessibility and use of antivenom for snakebite envenomation in Africa with proposed strategies to overcome the limitations","authors":"Mahmood Muazu Dalhat ,&nbsp;Julien Potet ,&nbsp;Abdulaziz Mohammed ,&nbsp;Nafiisah Chotun ,&nbsp;Hanna Amanuel Tesfahunei ,&nbsp;Abdulrazaq Garba Habib","doi":"10.1016/j.toxcx.2023.100152","DOIUrl":null,"url":null,"abstract":"<div><p>Africa remains one of the regions with the highest incident and burden of snakebite. The goal of the World Health Organization to halve the global burden of snakebite by 2030 can only be achieved if sub-optimal access to antivenoms in the most affected regions is addressed. We identified upstream, midstream, and downstream factors along the antivenom value chain that prevent access to antivenoms in the African region. We identified windows of opportunities that could be utilized to ensure availability, accessibility, and affordability for snakebite endemic populations in Africa. These include implementation of multicomponent strategies such as intensified advocacy, community engagement, healthcare worker trainings, and leveraging the institutional and governance structure provided by African governments to address the challenges identified.</p></div>","PeriodicalId":37124,"journal":{"name":"Toxicon: X","volume":null,"pages":null},"PeriodicalIF":3.6000,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/71/62/main.PMC10015232.pdf","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Toxicon: X","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2590171023000048","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"TOXICOLOGY","Score":null,"Total":0}
引用次数: 2

Abstract

Africa remains one of the regions with the highest incident and burden of snakebite. The goal of the World Health Organization to halve the global burden of snakebite by 2030 can only be achieved if sub-optimal access to antivenoms in the most affected regions is addressed. We identified upstream, midstream, and downstream factors along the antivenom value chain that prevent access to antivenoms in the African region. We identified windows of opportunities that could be utilized to ensure availability, accessibility, and affordability for snakebite endemic populations in Africa. These include implementation of multicomponent strategies such as intensified advocacy, community engagement, healthcare worker trainings, and leveraging the institutional and governance structure provided by African governments to address the challenges identified.

Abstract Image

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
抗蛇毒血清在非洲的可用性、可及性和使用情况,以及克服限制的拟议策略
非洲仍然是毒蛇咬伤事件和负担最高的地区之一。只有解决受影响最严重地区获得抗蛇毒血清的次优途径问题,世界卫生组织到2030年将全球毒蛇咬伤负担减半的目标才能实现。我们确定了抗蛇毒血清价值链上阻碍非洲地区获得抗蛇毒血清的上游、中游和下游因素。我们确定了可用于确保非洲蛇咬伤流行人群的可用性、可及性和可负担性的机会窗口。其中包括实施多要素战略,如加强宣传、社区参与、医护人员培训,以及利用非洲政府提供的体制和治理结构来应对已确定的挑战。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Toxicon: X
Toxicon: X Pharmacology, Toxicology and Pharmaceutics-Toxicology
CiteScore
6.50
自引率
0.00%
发文量
33
审稿时长
14 weeks
期刊最新文献
Stress levels, hematological condition, and productivity of plasma-producing horses used for snake antivenom manufacture: A comparison of two industrial bleeding methods Diagnosis of human envenoming by terrestrial venomous animals: Routine, advances, and perspectives Supplementation of polyclonal antibodies, developed against epitope-string toxin-specific peptide immunogens, to commercial polyvalent antivenom, shows improved neutralization of Indian Big Four and Naja kaouthia snake venoms Bioprospection of rattlesnake venom peptide fractions with anti-adipose and anti-insulin resistance activity in vitro A probabilistic hazard assessment for cyanobacterial toxins accounting for regional geography and water body trophic status
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1