{"title":"Granular cell odontogenic tumour: Case report and review of literature","authors":"Carolina Cavaliéri Gomes, Marcelo Drummond Naves, Marcos Vinício Pereira, Luciano Marques Silva, Ricardo Alves Mesquita, Ricardo Santiago Gomez","doi":"10.1016/j.ooe.2006.07.001","DOIUrl":null,"url":null,"abstract":"<div><p>Granular cell odontogenic tumour (GCOT) is a rare benign odontogenic neoplasm composed of granular cells and ameloblastic epithelium. The GCOT tends to occur in the posterior region of the mandible, especially in 50-year-old women. We report a case of GCOT that occurred in the mandible of a 20-year-old woman. Immunohistochemically, while a low proliferating cell nuclear antigen (PCNA) staining was observed in the granular cells, the epithelium showed a significant PCNA labelling, which suggests that the odontogenic epithelium may have an important role on the GCOT tumorigenesis.</p></div>","PeriodicalId":100990,"journal":{"name":"Oral Oncology Extra","volume":"42 8","pages":"Pages 277-280"},"PeriodicalIF":0.0000,"publicationDate":"2006-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ooe.2006.07.001","citationCount":"8","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oral Oncology Extra","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1741940906000148","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 8
Abstract
Granular cell odontogenic tumour (GCOT) is a rare benign odontogenic neoplasm composed of granular cells and ameloblastic epithelium. The GCOT tends to occur in the posterior region of the mandible, especially in 50-year-old women. We report a case of GCOT that occurred in the mandible of a 20-year-old woman. Immunohistochemically, while a low proliferating cell nuclear antigen (PCNA) staining was observed in the granular cells, the epithelium showed a significant PCNA labelling, which suggests that the odontogenic epithelium may have an important role on the GCOT tumorigenesis.
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