Preparation and characterization of zein-based core-shell nanoparticles for encapsulation and delivery of hydrophobic nutrient molecules: Enhancing environmental stress resistance and antioxidant activity

IF 11 1区农林科学 Q1 CHEMISTRY, APPLIED Food Hydrocolloids Pub Date : 2023-11-09 DOI:10.1016/j.foodhyd.2023.109524

Zhiheng Zhang , Yaxu Meng , Jinpeng Wang , Chao Qiu , Wenbo Miao , Qianzhu Lin , Xiaojing Li , Shangyuan Sang , David Julian McClements , Aiquan Jiao , Zhengyu Jin

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Abstract

A simple reverse solvent co-precipitation method was designed to prepare zein/debranched oxidized starch core-shell composite nanoparticles. Studies have shown that the composite nanoparticles have good stability and the ability to protect resveratrol from chemical degradation during long-term storage, pasteurization, and ultraviolet irradiation. The encapsulation rate of resveratrol in composite nanoparticles (81.15%) was significantly higher than that of pure protein nanoparticles (47.15%). The results of FT-IR (fourier transform infrared spectroscopy), circular dichroism, and fluorescence spectra show that hydrogen bonding, hydrophobic interaction, and electrostatic interaction exist in the composite nanoparticles. Under pasteurization conditions, ultraviolet radiation, and two weeks of room-temperature storage, the composite nanoparticles can better maintain the biological activity of nutrient molecules. Moreover, the particles can maintain stability in different pH and ionic strength environments and gradually degrade and release active molecules in the intestinal tract in vitro in the simulated gastrointestinal environment. These results show that zein/debranched oxidized starch nanoparticles (ZDNPs) have great potential for application in the fields of functional drinks, food, and biomedicine-related delivery.

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玉米蛋白基核壳纳米颗粒的制备与表征:用于包封和递送疏水营养分子:增强环境抗逆性和抗氧化活性

设计了一种简单的反溶剂共沉淀法制备玉米蛋白/脱支氧化淀粉核壳复合纳米颗粒。研究表明，复合纳米颗粒在长期储存、巴氏灭菌和紫外线照射过程中具有良好的稳定性和保护白藜芦醇免受化学降解的能力。复合纳米颗粒对白藜芦醇的包封率(81.15%)显著高于纯蛋白质纳米颗粒的包封率(47.15%)。傅里叶变换红外光谱(FT-IR)、圆二色性和荧光光谱结果表明，复合纳米颗粒中存在氢键、疏水相互作用和静电相互作用。复合纳米颗粒在巴氏杀菌、紫外线照射、室温保存两周的条件下，能较好地保持营养分子的生物活性。此外，颗粒在不同pH值和离子强度的环境中都能保持稳定，并在体外模拟胃肠道环境中逐渐降解并释放出肠道内的活性分子。这些结果表明，玉米蛋白/脱支氧化淀粉纳米颗粒(ZDNPs)在功能饮料、食品和生物医学相关的递送领域具有巨大的应用潜力。

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来源期刊

Food Hydrocolloids 工程技术-食品科技

CiteScore

19.90

自引率

14.00%

发文量

871

审稿时长

37 days

期刊介绍： Food Hydrocolloids publishes original and innovative research focused on the characterization, functional properties, and applications of hydrocolloid materials used in food products. These hydrocolloids, defined as polysaccharides and proteins of commercial importance, are added to control aspects such as texture, stability, rheology, and sensory properties. The research's primary emphasis should be on the hydrocolloids themselves, with thorough descriptions of their source, nature, and physicochemical characteristics. Manuscripts are expected to clearly outline specific aims and objectives, include a fundamental discussion of research findings at the molecular level, and address the significance of the results. Studies on hydrocolloids in complex formulations should concentrate on their overall properties and mechanisms of action, while simple formulation development studies may not be considered for publication. The main areas of interest are: -Chemical and physicochemical characterisation Thermal properties including glass transitions and conformational changes- Rheological properties including viscosity, viscoelastic properties and gelation behaviour- The influence on organoleptic properties- Interfacial properties including stabilisation of dispersions, emulsions and foams- Film forming properties with application to edible films and active packaging- Encapsulation and controlled release of active compounds- The influence on health including their role as dietary fibre- Manipulation of hydrocolloid structure and functionality through chemical, biochemical and physical processes- New hydrocolloids and hydrocolloid sources of commercial potential. The Journal also publishes Review articles that provide an overview of the latest developments in topics of specific interest to researchers in this field of activity.