Combining impact monitoring mouthguards and blood biomarkers to monitor head impacts among Muay Thai athletes – A case study

JSAMS plus Pub Date : 2023-01-01 DOI:10.1016/j.jsampl.2023.100044

Mikael Swarén , Joel Simrén , Hanna Huber , Henrik Zetterberg

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Abstract

Objective

To investigate the relationship between head impact characteristics and the levels of blood biomarkers associated with brain injury, neurofilament light (NfL) and glial fibrillary acidic protein (GFAP).

Methods

Four elite amateur Muay Thai athletes were equipped with impact monitoring mouthguards, collecting linear and rotational acceleration data during a period of eight weeks. Capillary blood samples were collected after each period of sparring sessions to analyse the levels of NfL and GFAP.

Results

On a group level, mean GFAP levels were negatively correlated to mean impacts per session (p < 0.05). Two athletes had significant correlations between head impact characteristics and the levels of NfL and/or GFAP.

Conclusions

The results indicate that NfL and GFAP might responded differently to linear and rotational accelerations and/or that the effect of different types of accelerations on brain tissue integrity is individual. The methods used could be useful to monitor brain health in different impacts sports.

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结合影响监测护齿和血液生物标志物监测泰拳运动员头部影响的案例研究

目的探讨头部撞击特征与脑损伤相关血液标志物、神经丝光(NfL)和胶质纤维酸性蛋白(GFAP)水平的关系。方法选取4名优秀的业余泰拳运动员，在8周的时间内，为其配备冲击监测护齿，收集线性和旋转加速度数据。每次训练结束后采集毛细血管血样，分析NfL和GFAP水平。结果在组水平上，平均GFAP水平与每次会议的平均影响呈负相关(p <0.05)。两名运动员的头部撞击特征与NfL和/或GFAP水平之间存在显著相关性。结论NfL和GFAP对线性和旋转加速度的反应可能不同，或者不同类型的加速度对脑组织完整性的影响是个体的。所使用的方法可以用于监测不同影响运动的大脑健康。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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