A novel network approach to multiscale biological regulation.

IF 9 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Cell Systems Pub Date : 2023-03-15 DOI:10.1016/j.cels.2023.02.004

Guido Gigante, Alessandro Giuliani, Maurizio Mattia

引用次数: 2

Abstract

Modeling systems at multiple interacting scales is probably the most relevant task for pursuing a physically motivated explanation of biological regulation. In a new study, Smart and Zilman develop a convincing, albeit preliminary, model of the interplay between the cell microscale and the macroscopic tissue organization in biological systems.

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多尺度生物调控的新网络方法。

在多个相互作用的尺度上对系统进行建模可能是追求生物调节的物理动机解释的最相关的任务。在一项新的研究中，Smart和Zilman开发了一个令人信服的模型，尽管是初步的，在生物系统中细胞微观尺度和宏观组织组织之间的相互作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cell Systems Medicine-Pathology and Forensic Medicine

CiteScore

16.50

自引率

1.10%

发文量

审稿时长

42 days

期刊介绍： In 2015, Cell Systems was founded as a platform within Cell Press to showcase innovative research in systems biology. Our primary goal is to investigate complex biological phenomena that cannot be simply explained by basic mathematical principles. While the physical sciences have long successfully tackled such challenges, we have discovered that our most impactful publications often employ quantitative, inference-based methodologies borrowed from the fields of physics, engineering, mathematics, and computer science. We are committed to providing a home for elegant research that addresses fundamental questions in systems biology.