Diabetes and TB: Confluence of Two Epidemic and Its Effect on Clinical Presentation.

IF 2.4 Q3 ENDOCRINOLOGY & METABOLISM Current diabetes reviews Pub Date : 2024-01-01 DOI:10.2174/1573399819666230331113156
Kumudha Dhamotharaswamy, Hemalatha Selvaraj, Padmashree Lakshmanaperumal, R Harsha, Anuja S Sasankan, Prabha Thangavelu, K Menaka, Sivakumar Thangavel
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Abstract

Background: Tuberculosis (TB) has become a rising concern in low-income countries, particularly in those with Human Immuno Deficiency Virus (HIV) epidemics, and type 2 diabetes has emerged as a significant global chronic health problem, owing to increases in obesity, lifestyle changes, and ageing populations. Diabetes has been identified as a major risk factor for the development of TB. Despite the fact that diabetes imparts a substantially lower risk of TB (3-fold) as compared to HIV (>20-fold), in communities where the number of DM patients is high, the contribution of diabetes to TB might be bigger than HIV.

Methods: This review will focus on the link between TB and diabetes, which is now one of the most important topics for physicians since diabetes impacts the clinical presentation and outcome of TB and vice versa.

Results: Though TB is more common in type 1 diabetes, the extent of the problem in type 2 diabetes should be taken into account with equal care, as type 2 diabetes affects a substantially higher number of individuals.

Conclusions: Diabetes patients are more vulnerable to infections because of their impaired immune systems. Increased glucose level leads to a rise in the infection status among TB patients and also leads to a rise in various complications. Extensive and increased screening for both TB and DM over years can help diagnose disease priorly and help in better management. TB, when diagnosed in its early stages, can be easily eradicated.

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糖尿病与肺结核:两种流行病的交汇及其对临床表现的影响。
背景:在低收入国家,尤其是在人类免疫缺陷病毒(HIV)流行的国家,结核病(TB)已成为一个日益严重的问题,而由于肥胖症的增加、生活方式的改变和人口老龄化,2 型糖尿病已成为一个重要的全球性慢性健康问题。糖尿病已被确定为肺结核发病的主要风险因素。尽管与艾滋病病毒(>20 倍)相比,糖尿病导致结核病的风险要低得多(3 倍),但在糖尿病患者较多的社区,糖尿病对结核病的影响可能比艾滋病病毒更大:本综述将重点探讨肺结核与糖尿病之间的联系,由于糖尿病会影响肺结核的临床表现和治疗效果,反之亦然,因此肺结核与糖尿病之间的联系已成为医生最关心的话题之一:尽管肺结核在 1 型糖尿病患者中更为常见,但由于 2 型糖尿病患者的人数远远高于 1 型糖尿病患者,因此应同等重视 2 型糖尿病患者的肺结核问题:结论:糖尿病患者由于免疫系统受损,更容易受到感染。血糖水平升高会导致肺结核患者的感染率上升,同时也会导致各种并发症的增加。多年来,对肺结核和糖尿病进行广泛和更多的筛查有助于提前诊断疾病,并帮助进行更好的治疗。结核病如果在早期得到诊断,很容易被根除。
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来源期刊
Current diabetes reviews
Current diabetes reviews ENDOCRINOLOGY & METABOLISM-
CiteScore
6.30
自引率
0.00%
发文量
158
期刊介绍: Current Diabetes Reviews publishes frontier reviews on all the latest advances on diabetes and its related areas e.g. pharmacology, pathogenesis, complications, epidemiology, clinical care, and therapy. The journal"s aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all researchers and clinicians who are involved in the field of diabetes.
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