Zhang Weishen: A Pioneer in the Development and Industrial Production of Penicillin in New China

Q2 Medicine Chinese Medical Sciences Journal Pub Date : 2022-09-01 DOI:10.24920/004084
Bin Yu, Fumin Huang, Guoxing Tang, Jing Liu
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Abstract

The research and development of penicillin started with difficulty before 1949 and achieved certain results. In 1951, after the founding of the People's Republic of China, Zhang Weishen, as the only Chinese scientist who had been trained and worked in a penicillin research and development center in the United States for many years, overcame many difficulties and returned to China. In 1953, with the efforts of Zhang Weishen and his colleagues, China realized the industrialized production of penicillin, alleviating the urgent needs of the masses. Antibiotics has also become the first discipline to achieve major scientific and technological achievements after the founding of the New China. In the mid-1950s, the technical breakthrough in the localization of lactose substitutes marked the localization of the raw materials of the penicillin-producing culture medium, which paved the way for the industrialized production of penicillin with Chinese characteristics. Antibiotics have become one of the most widely used and affordable drugs for hundreds of millions of patients in China, and China has since ended the humiliating history of the “Sick Man of East Asia".

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张维深:新中国盘尼西林开发和工业化生产的先驱者
1949年以前,盘尼西林的研究开发起步困难,取得了一定的成果。1951年,中华人民共和国成立后,张维深作为唯一一个在美国青霉素研发中心接受培训和工作多年的中国科学家,克服重重困难回到了中国。1953年,在张维深等人的努力下,中国实现了青霉素的工业化生产,缓解了群众的迫切需要。抗生素也成为新中国成立后第一个取得重大科技成果的学科。20世纪50年代中期,乳糖代用品国产化的技术突破,标志着产青霉素培养基原料的国产化,为中国特色青霉素的工业化生产铺平了道路。抗生素已成为中国数亿患者使用最广泛、负担得起的药物之一,中国从此结束了“东亚病夫”的耻辱历史。
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来源期刊
Chinese Medical Sciences Journal
Chinese Medical Sciences Journal Medicine-Medicine (all)
CiteScore
2.40
自引率
0.00%
发文量
1275
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