[A clinical case of occupational cutaneous tuberculosis in the healthcare field].

IF 1 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Anales Del Sistema Sanitario De Navarra Pub Date : 2022-11-21 DOI:10.23938/ASSN.1022
Asan Mollov, Laura Otano-Oroz, Belén Asenjo-Redin, Montserrat Ojer-Zapata
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Abstract

Cutaneous tuberculosis is a rare extrapulmonary pre-sentation of tuberculosis, caused by mycobacterial species of the Mycobacterium tuberculosis complex. We describe a case of cutaneous tuberculosis in a 57-year-old technician from the microbiology laboratory in our hospital. She accidentally experienced a needlestick injury with a hollow needle while at work. Skin lesion developed shortly after on the punctured finger. A biopsy was performed, revealing necrotizing (caseating) granulomatous inflammation. Pharmacological treatment was initiated with four standard drugs: isoniazid, rifampicin, pyrazinamide, and ethambutol hydrochloride. Improvement was observed, but the initial treatment had to be suspended due to intolerance to some of the drugs and changed to a treatment with isoniazid, rifampicin, and levofloxacin. The long duration of the treatment may increase the risk of toxic effects, making it necessary to discard the drug causing these effects and change the treatment regimen.

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【卫生保健领域职业性皮肤结核临床一例】。
皮肤结核是一种罕见的肺外结核的先兆,由结核分枝杆菌复合体的分枝杆菌种类引起。我们报告一个57岁的皮肤结核病例,来自我们医院微生物实验室的技术人员。她在工作时不小心被空心针刺伤了。被刺破的手指上很快出现了皮肤损伤。活检显示坏死性肉芽肿性炎症。药物治疗开始使用四种标准药物:异烟肼、利福平、吡嗪酰胺和盐酸乙胺丁醇。观察到改善,但由于对某些药物不耐受,最初的治疗不得不暂停,改为异烟肼、利福平和左氧氟沙星治疗。长时间的治疗可能会增加毒性作用的风险,因此有必要放弃引起这些作用的药物并改变治疗方案。
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来源期刊
Anales Del Sistema Sanitario De Navarra
Anales Del Sistema Sanitario De Navarra 医学-公共卫生、环境卫生与职业卫生
CiteScore
1.30
自引率
30.00%
发文量
88
审稿时长
>12 weeks
期刊介绍: La revista Anales del Sistema Sanitario de Navarra es una revista de contenido médico sanitario de carácter generalista. En ella tienen cabida artículos referidos a temas de salud/enfermedad en general, salud pública, administración y gestión sanitaria y Atención Primaria de salud.
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