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Bilateral subgaleal hematoma after a robot-assisted radical prostatectomy: an uncommon complication. 机器人辅助根治性前列腺切除术后双侧声门下血肿:一种罕见的并发症。
IF 1 4区 医学 Q3 Medicine Pub Date : 2023-08-31 DOI: 10.23938/ASSN.1047
Iñigo Rubio Baines, Antonio Martínez Simón, Francisco Javier Ancizu, Isidro Olavide, Cristina Honorato-Cía

Robot-assisted radical prostatectomy is a relatively recent technique. Its advantages include less invasiveness and better pain management, but has specific anesthesia requirements, such as steep Trendelenburg position and pneumoperitoneum. Mild complications are common, e.g., transient hypotension or soft tissue edema. We present a case of a 62-year old male who developed subgaleal hematoma associated with transient neurologic impairment after surgery. Jugular vein insufficiency was suspected as the most likely cause. The patient recovered fully. Robot-assisted radical prostatectomy can be a challenging procedure due to the anesthesia requirements, but most complications are mild and transient. However, patients should be carefully assessed before surgery. We identified potential factors that may have led to this complication: the abnormal prolonged surgical time, the steep Trendelenburg, a non-assessed jugular vein insufficiency, and/or patient`s obesity.

机器人辅助前列腺根治术是一项相对较新的技术。它的优点包括侵入性小,疼痛管理更好,但有特定的麻醉要求,如陡峭的特伦德伦堡体位和气腹。常见轻度并发症,如短暂性低血压或软组织水肿。我们报告了一例62岁的男性患者,他在手术后出现了与短暂神经损伤相关的声门下血肿。颈静脉功能不全被怀疑是最可能的原因。病人完全康复了。由于麻醉要求,机器人辅助前列腺根治术可能是一项具有挑战性的手术,但大多数并发症都是轻微和短暂的。然而,手术前应仔细评估患者。我们确定了可能导致这种并发症的潜在因素:异常延长的手术时间、陡峭的特伦德伦堡、未经评估的颈静脉功能不全和/或患者肥胖。
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引用次数: 0
Effect of mouthwashes on the microhardness of aesthetic composite restorative materials. 漱口水对美容复合修复材料显微硬度的影响。
IF 1 4区 医学 Q3 Medicine Pub Date : 2023-08-30 DOI: 10.23938/ASSN.1049
Noura Abdulaziz Alessa

Background: Mouthwashes are increasingly being used worldwide. However, these preparations are known to have a negative impact on composite resin dental restorations. In this study, we aim to evaluate the effect of mouthwashes on the microhardness of such restorations.

Methods: Thirty specimens of Tetric N-Ceram composite were prepared. Each composite specimen was cured for 40 seconds and kept in saline solution for 24 hours at 37 °C. Baseline microhardness of each specimen was recorded using an Innovatest Vickers Micro Hardness Tester. Composite specimens were randomly placed in 20 mL of the selected mouthwashes (Colgate® Plax, Listerine® Teeth & Gum Defence, and Closeup® Antibacterial Mouthwash Cool Breeze) and stored in an incubator for 24 hours at 37 °C. Next, microhardness values were rechecked. pH measurements were recorded for each type of mouthwash using a digital pH meter.

Results: Due to the acidic nature of Colgate® and Listerine®, the microhardness of the restorations decreased with these mouthwashes; Listerine® caused the greatest decrease in microhardness and had the lowest pH reading (4.34). For Closeup®, with a neutral pH (7.02), no negative effect on microhardness was found; on the contrary, due to the presence of zinc in this latter mouthwash, an increase of the microhardness was found.

Conclusions: We confirm the negative effect of acidic mouthwashes on the microhardness of composite dental restorations.

背景:漱口水在世界范围内的使用越来越多。然而,已知这些制剂对复合树脂牙科修复体具有负面影响。在这项研究中,我们旨在评估漱口水对这种修复体显微硬度的影响。方法:制备了30个Tetric N-Ceram复合材料样品。每个复合材料样品固化40秒,并在37°C的盐水溶液中保持24小时。使用Innovatest维氏显微硬度计记录每个试样的基线显微硬度。将复合样本随机放入20 mL选定的漱口水(高露洁®Plax、利斯特林®牙齿和牙龈防护以及Closeup®抗菌漱口水Cool Breeze)中,并在37°C的培养箱中储存24小时。接下来,重新检查显微硬度值。使用数字pH计记录每种类型漱口水的pH测量值。结果:由于高露洁®和利斯特林®的酸性性质,这些漱口水降低了修复体的显微硬度;Listerine®引起的显微硬度下降最大,pH读数最低(4.34)。对于Closeup®,中性pH(7.02),未发现对显微硬度的负面影响;相反,由于锌在后一种漱口水中的存在,发现显微硬度增加。结论:酸性漱口水对复合修复体显微硬度有负面影响。
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引用次数: 0
Psychometric analysis of the Psychiatric Diagnostic Screening Questionnaire (PDSQ) and determinants of psychopathology in two outpatient clinics in Navarre (Spain). 纳瓦拉(西班牙)两个门诊的精神病诊断筛查问卷(PDSQ)和精神病理学决定因素的心理测量分析。
IF 1 4区 医学 Q3 Medicine Pub Date : 2023-08-30 DOI: 10.23938/ASSN.1043
Juan I Arrarás, Manuel J Cuesta, Victor Peralta, Gustavo J Gil-Berrozpe, Laura Barrado, Olga Correa, Rebeca Elorza, Lorea González, Irma Garmendia, Lucía Janda, Patricia Macaya, Camino Núñez, Pablo Sabater, Aileen Torrejon

Background: The self-report Psychiatric Diagnostic Screening Questionnaire PDSQ is designed to screen Axis I psychiatric disorders. We aim to determine its psychometric properties in Spanish outpatients and assess its relationship with two interviews (for psychopathology and for personality disorders) and clinical/demographic variables.

Methodology: We administered the study questionnaire, the Mini International Neuropsychiatric Interview Plus (MINI-Plus), the Standardised Assessment of Personality Abbreviated Scale (SAPAS), and the List of Threatening Experiences Questionnaire (LTE-Q) to 375 patients at two public outpatient centres. Reliability of the study questionnaire was evaluated (Cronbach's alpha, ?) and known-group validity measured by comparing groups based on demographic and clinical variables (binary logistic regression analysis) and MINI-Plus diagnoses (Mann-Whitney U). The diagnostic accuracy of the study questionnaire score was analysed taking the MINI-Plus diagnoses as the gold standard (ROC analysis).

Results: Internal consistency was adequate across all PDSQ scales (? >0.7; mean ?=0.85). Known-group comparisons were satisfactory. Female and male patients showed higher prevalence of internalizing and externalizing diagnoses, respectively. Younger age, more life events and limitations, higher SAPAS scores, and lower economic levels were linked to a greater number of PDSQ diagnoses. Inter-group differences were found for all PDSQ scales based on the corresponding MINI-Plus diagnoses. Mean values of sensitivity, AUC, and negative predictive value were 88.7, 0.82, and 96.7, respectively.

Conclusions: When applied to a sample of Spanish outpatients, the PDSQ exhibits satisfactory psychometric properties and adequate relationships with the psychopathology and personality interviews, and clinical and demographic variables. The study questionnaire is suitable for assessing comorbidity and psychopathology dimensions.

背景:自我报告的精神病诊断筛查问卷PDSQ旨在筛查Axis I精神障碍。我们的目的是确定其在西班牙门诊患者中的心理测量特性,并评估其与两次访谈(精神病理学和人格障碍)和临床/人口统计学变量的关系。方法:我们对两个公共门诊中心的375名患者进行了研究问卷、迷你国际神经心理访谈+(Mini-Plus)、人格缩写标准化评估量表(SAPAS)和威胁经历清单问卷(LTE-Q)。根据人口统计学和临床变量(二元逻辑回归分析)和MINI Plus诊断(Mann-Whitney U),评估研究问卷的可靠性(Cronbach’s alpha,?),并通过比较各组来测量已知组的有效性。以MINI Plus诊断为金标准分析研究问卷评分的诊断准确性(ROC分析)。结果:所有PDSQ量表的内部一致性都足够(?>0.7;平均值?=0.85)。已知的组间比较令人满意。女性和男性患者分别表现出较高的内化和外化诊断患病率。年龄较小、生活事件和限制较多、SAPAS评分较高、经济水平较低与PDSQ诊断数量较多有关。基于相应的MINI Plus诊断,所有PDSQ量表均存在组间差异。敏感性、AUC和阴性预测值的平均值分别为88.7、0.82和96.7。结论:当应用于西班牙门诊患者样本时,PDSQ表现出令人满意的心理测量特性,并与精神病理学和人格访谈以及临床和人口统计学变量有充分的关系。研究问卷适用于评估共病和精神病理学维度。
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引用次数: 0
[Prevalence of dental and mucosal lesions among the pediatric population who attended the emergency department of a general hospital]. [在综合医院急诊科就诊的儿科人群中,牙齿和粘膜病变的患病率]。
IF 1 4区 医学 Q3 Medicine Pub Date : 2023-08-28 DOI: 10.23938/ASSN.1041
Montserrat Suárez Ardura, María García-Pola, José Manuel Cuervo Menéndez

Background: The high prevalence of oral pathology in children encourages to gain further understanding on their manifestations and urgent nature, objective of the present study Methodology. Cross-sectional study that included patients aged <14 years of age who attended an emergency department over a one-year period. The relationship between the variables collected and oral pathology was analyzed.

Results: Fifty-five patients were included, 45.5% girls, mean age 4.11 years (10 days to 13 years). Overall, mucosal pathology (74.5%) prevailed over dental ones, and lesions of infectious origin (54.6%) over the traumatic ones (14.5%). Dental pathology (50% toothache and 35.7% infections) was significantly associated with being >6 years (66.7 vs 10%), pain (40.7 vs 10.7%) and absence of fever (37.9 vs 11.5%). Mucosal pathology (61% infections: 53.7% viral and 31.7% due to herpangina) was significantly associated with being =6 years (60 vs 6.7%) and having fever (76.9 vs 17.2%). Six traumatic lesions on the mucosa and two on the teeth were observed; significantly more patients attended the emergency room within 24 hours (median =1 hour) than in the case of infection (100 vs 51.7%). Being =6 years was significantly associated with fever, mucosal pathology, mucosal infection, and herpangina, and being >6 years was associated with pain, previous antibiotic treatment and at discharge, and previous NSAID regimen.

Conclusions: The analyzed pediatric oral pathologies treated in the emergency department are of mucosal and infectious origin. Dental disease prevail in children >6 years of age and mucosal lesions in those =6 years; no sex differences are observed.

背景:儿童口腔病理学的高患病率促使我们进一步了解其表现和紧迫性,这是本研究方法的目的。包括年龄段患者的横断面研究结果:包括55名患者,45.5%为女孩,平均年龄4.11岁(10天至13岁)。总体而言,粘膜病理学(74.5%)高于口腔病理学,感染性病变(54.6%)高于创伤性病变(14.5%)。口腔病理学(50%牙痛和35.7%感染)与>6岁显著相关(66.7%vs10%),疼痛(40.7%对10.7%)和不发烧(37.9%对11.5%)。粘膜病理学(61%感染:53.7%为病毒性感染,31.7%由穿山甲引起)与年龄=6岁(60%对6.7%)和发烧(76.9%对17.2%)显著相关。观察到6个粘膜损伤和2个牙齿损伤;在24小时内(中位数=1小时)到急诊室就诊的患者明显多于感染病例(100vs51.7%)。年龄=6岁与发烧、粘膜病理、粘膜感染和穿山甲显著相关,年龄>6岁与疼痛、既往抗生素治疗和出院以及既往非甾体抗炎药方案相关。结论:在急诊科治疗的儿童口腔病理分析是粘膜和感染性的。牙科疾病在6岁以上的儿童中普遍存在,在6岁以下的儿童中存在粘膜病变;没有观察到性别差异。
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引用次数: 0
[Breastfeeding and rooming-in in the management of neonatal abstinence syndrome. Scoping review]. [母乳喂养和留宿治疗新生儿禁欲综合征。范围界定综述]。
IF 1 4区 医学 Q3 Medicine Pub Date : 2023-08-28 DOI: 10.23938/ASSN.1048
Paula Baeza-Gozalo, Sara Sola-Cía, Olga López-Dicastillo

At present, more babies are born with neonatal abstinence syndrome due to the increased use of certain substances by their mothers while pregnant. The therapeutic approaches for this syndrome vary in clinical practice, and in some centres, breastfeeding and rooming-in are interrupted. The aim of this work was to analyse the effects of breastfeeding and rooming-in in infants with neonatal abstinence syndrome by conducting a scoping review of the related literature in PubMed and CINAHL. Eleven papers were included, which showed that breastfeeding and rooming-in reduced hospital stay and the need for and duration of pharmacological treatment. In addition, rooming-in decreased the likelihood of admission to the Neonatal Intensive Care Unit, although there was no improvement of the severity of neonatal abstinence syndrome signs. Breastfed infants had milder withdrawal signs and, although they were more likely to be readmitted than formula-fed infants were, there were no statistically significant differences. There was no evidence that rooming-in decreased hospital readmission after discharge. Our findings support the maintenance of cohabitation and breastfeeding whenever possible in the management of this neonatal abstinence syndrome, so as not to worsen the conditions of the neonate, while introducing measures to ensure mother-child safety.

目前,由于母亲在怀孕期间越来越多地使用某些物质,越来越多的婴儿出生时患有新生儿禁欲综合征。这种综合征的治疗方法在临床实践中各不相同,在一些中心,母乳喂养和住宿被中断。这项工作的目的是通过对PubMed和CINAHL的相关文献进行范围审查,分析母乳喂养和留宿对新生儿禁欲综合征婴儿的影响。纳入了11篇论文,这些论文表明母乳喂养和室友减少了住院时间,减少了药物治疗的需要和持续时间。此外,尽管新生儿禁欲综合征症状的严重程度没有改善,但入住房间降低了入住新生儿重症监护室的可能性。母乳喂养的婴儿戒断症状较轻,尽管他们比配方奶粉喂养的婴儿更有可能再次入院,但没有统计学上的显著差异。没有证据表明在医院住一个房间可以减少出院后的再次入院。我们的研究结果支持在管理这种新生儿禁欲综合征时尽可能保持同居和母乳喂养,以免恶化新生儿的状况,同时采取措施确保母子安全。
{"title":"[Breastfeeding and rooming-in in the management of neonatal abstinence syndrome. Scoping review].","authors":"Paula Baeza-Gozalo,&nbsp;Sara Sola-Cía,&nbsp;Olga López-Dicastillo","doi":"10.23938/ASSN.1048","DOIUrl":"10.23938/ASSN.1048","url":null,"abstract":"<p><p>At present, more babies are born with neonatal abstinence syndrome due to the increased use of certain substances by their mothers while pregnant. The therapeutic approaches for this syndrome vary in clinical practice, and in some centres, breastfeeding and rooming-in are interrupted. The aim of this work was to analyse the effects of breastfeeding and rooming-in in infants with neonatal abstinence syndrome by conducting a scoping review of the related literature in PubMed and CINAHL. Eleven papers were included, which showed that breastfeeding and rooming-in reduced hospital stay and the need for and duration of pharmacological treatment. In addition, rooming-in decreased the likelihood of admission to the Neonatal Intensive Care Unit, although there was no improvement of the severity of neonatal abstinence syndrome signs. Breastfed infants had milder withdrawal signs and, although they were more likely to be readmitted than formula-fed infants were, there were no statistically significant differences. There was no evidence that rooming-in decreased hospital readmission after discharge. Our findings support the maintenance of cohabitation and breastfeeding whenever possible in the management of this neonatal abstinence syndrome, so as not to worsen the conditions of the neonate, while introducing measures to ensure mother-child safety.</p>","PeriodicalId":7775,"journal":{"name":"Anales Del Sistema Sanitario De Navarra","volume":"46 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e0/12/assn-46-02-e1048.PMC10518805.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10492998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Distal ventriculoperitoneal shunt catheter migration into the pulmonary artery: a rare complication]. [远端脑室-腹腔分流导管迁移至肺动脉:一种罕见的并发症]。
IF 1 4区 医学 Q3 Medicine Pub Date : 2023-08-24 DOI: 10.23938/ASSN.1046
Pelayo Hevia-Rodríguez, Mikel Armendariz-Guezala, José Undabeitia-Huertas

Ventriculoperitoneal shunt placement is a common treatment for hydrocephalus, although not devoid of complications. We report a case of a 60-year-old male who underwent ventriculoperitoneal shunt implantation for the treatment of post-traumatic hydrocephalus. Thirteen months post- surgery, after an initial clinical improvement, the patient manifested gait and cognitive disorders. Chest X-rays and computed tomography revealed that the distal shunt catheter had migrated into the pulmonary artery. The catheter was removed by reopening the previous retroauricular incision followed by manual traction, without incidents. A new peritoneal catheter was implanted with immediate clinical improvement and no further complications two years after the second surgery. We communicate a rare complication of a standard neurosurgical procedure that can be detected by different healthcare professionals, and review its various forms of presentation and multidisciplinary management strategies from 19 similar clinical cases found in the literature.

脑室-腹腔分流术是治疗脑积水的常用方法,尽管并非没有并发症。我们报告了一例60岁的男性患者,他接受了脑室-腹腔分流术治疗创伤后脑积水。术后13个月,在初步的临床改善后,患者出现步态和认知障碍。胸部X光片和计算机断层扫描显示,远端分流导管已迁移到肺动脉中。通过重新打开先前的耳后切口,然后进行手动牵引,移除了导管,没有发生任何意外。在第二次手术后两年,植入了一根新的腹膜导管,临床立即得到改善,没有出现进一步的并发症。我们介绍了不同医疗专业人员可以检测到的标准神经外科手术的一种罕见并发症,并回顾了文献中发现的19例类似临床病例的各种表现形式和多学科管理策略。
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引用次数: 0
[The future of public health after the pandemic. A window of opportunity]. [新冠疫情后公共卫生的未来。机会之窗]。
IF 1 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-08-22 DOI: 10.23938/ASSN.1045
Salvador Peiró
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引用次数: 0
[Survival of cancer patients in Navarre and comparison with Spain]. [纳瓦拉地区癌症患者的生存率及与西班牙的比较]。
IF 1 4区 医学 Q3 Medicine Pub Date : 2023-08-16 DOI: 10.23938/ASSN.1042
Marcela Guevara, Miren Baztan, Rosana Burgui, Alberto Ovies, Aitziber Menéndez, Maribel Eciolaza, Conchi Moreno-Iribas, Eva Ardanaz

Background: To analyze the survival of adult cancer patients in Navarre, describe its trend, and compare the data for this Spanish Autonomous Community against that reported for Spain.

Methods: Records of adult cancer patients were retrieved from the Navarre´s population-based cancer registry for two periods (1999-2007 and 2008-2016). The vital status had been updated to 2020. Observed survival, net survival and age-standardized net survival at five years with 95% confidence intervals were estimated overall and for twenty-nine cancer groups.

Results: We analyzed 57,564 cases. Age-standardized net survival was 59.9% (59.1-60.8) and 63.8% (62.8-64.7) for males and females diagnosed with cancer during the 2008-2016 period, respectively. Age-standardized net survival ranged from 13.4% (10.4-17.4) for pancreatic cancer to 94.0% (88.1-100) for thyroid cancer in male patients, and from 11.9% (7.2-19.7) for liver cancer to 95.6% (92.6-98.6-%) for thyroid cancer in female patients. Compared with cases diagnosed in the 1999-2007 period, age-standardized net survival increased in 10 cancer groups, resulting in an overall increase of 5.1 (4.1-6.0) percentage points. The age-standardized net survival in Navarre was 2.7 (1.9-3.4) percentage points higher than that described for Spain for the 2008-2013 period.

Conclusions: In Navarre, the survival of cancer patients diagnosed during the 2008-2016 period improved significantly in comparison to the 1999-2007 period. Different factors may explain this improvement, including earlier diagnoses, more effective treatment options, and better healthcare processes. Overall, survival was higher in women than in men. Our results suggest a higher survival rate in Navarre than in Spain.

背景:分析纳瓦拉成年癌症患者的生存率,描述其趋势,并将该西班牙自治区的数据与西班牙报告的数据进行比较。方法:从纳瓦拉基于人口的癌症登记处检索1999-2007年和2008-2016年两个时期的成年癌症患者记录。关键状态已更新为2020年。观察生存期,净生存期和年龄标准化净生存期为5年,95%置信区间为29个癌症组。结果:我们分析了57,564例病例。在2008-2016年期间,诊断为癌症的男性和女性的年龄标准化净生存率分别为59.9%(59.1-60.8)和63.8%(62.8-64.7)。男性胰腺癌患者的年龄标准化净生存率为13.4%(10.4-17.4)至94.0%(88.1-100),女性肝癌患者的年龄标准化净生存率为11.9%(7.2-19.7)至95.6%(92.6-98.6-%)。与1999-2007年期间诊断的病例相比,10个癌症组的年龄标准化净生存率增加,导致总体增加5.1(4.1-6.0)个百分点。2008-2013年期间,纳瓦拉的年龄标准化净生存率比西班牙高2.7(1.9-3.4)个百分点。结论:在纳瓦拉,2008-2016年期间诊断的癌症患者的生存率较1999-2007年期间显著提高。不同的因素可以解释这种改善,包括早期诊断、更有效的治疗方案和更好的医疗保健流程。总体而言,女性的存活率高于男性。我们的研究结果表明,纳瓦拉的存活率高于西班牙。
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引用次数: 0
[Risk factors for cancer-related cognitive impairment in breast and colorectal cancer patients who undergo chemotherapy]. [接受化疗的乳腺癌和结直肠癌患者癌症相关认知障碍的危险因素]。
IF 1 4区 医学 Q3 Medicine Pub Date : 2023-08-16 DOI: 10.23938/ASSN.1040
Patricia Iranzo, Ana Callejo, Julio Arbej, Sebastian Menao, Dolores Isla, Raquel Andrés

Background: Our study aims to evaluate the impact of different factors on cancer-related cognitive impairment in patients who undergo chemotherapy.

Methodology: Prospective longitudinal single-centre study that included patients with breast and colon carcinoma who underwent chemotherapy as part of their treatment. Clinical and genetic characteristics of the patients (single nucleotide polymorphisms, SNPs) were collected. Patients' neurocognitive status was assessed using eleven validated tests at three time points: before chemotherapy (M0 - baseline), between one and four weeks after completing chemotherapy (M1), and between 24-30 weeks after completing chemotherapy (M2).

Results: Sixty-two patients were included in this study; 82% were female, median age was 56 years (range 30-74), and 64.5% had been diagnosed with breast cancer. Overall, better cognitive results at M0 were associated with age < 55 years, higher educational level, absence of comorbidities, and the CC variant rs471692 (TOP2A). Significant decline was found between M0 to M1 in the Rey Auditory Verbal Learning Test and the Letter and Number test, with evidence of recovery in M2 compared to M0 regarding the following test: Visual Memory, Functioning Assessment Short Test (FAST), Digit Symbol Substitution and Cube. In the multivariate analysis, being =55 years of age, adjuvant chemotherapy, presence of comorbidities, tobacco and alcohol use, and GT variant rs1800795 were associated with cognitive decline between M0 and M1.

Conclusion: Being =55 years of age, female, presence of comorbidities and basic education level are related to a higher risk of cognitive impairment after chemotherapy.

背景:本研究旨在评估不同因素对化疗患者癌症相关认知障碍的影响。方法:前瞻性纵向单中心研究,包括接受化疗作为治疗一部分的乳腺癌和结肠癌患者。收集患者的临床和遗传特征(单核苷酸多态性,snp)。在化疗前(M0 -基线)、完成化疗后1 - 4周(M1)和完成化疗后24-30周(M2)三个时间点,使用11项有效的测试评估患者的神经认知状态。结果:本研究纳入62例患者;82%为女性,中位年龄为56岁(30-74岁),64.5%被诊断患有乳腺癌。总体而言,M0时较好的认知结果与年龄< 55岁、教育程度较高、无合共病和CC变异rs471692 (TOP2A)相关。在雷伊听觉语言学习测试和字母和数字测试中,发现M0到M1之间有显著下降,在以下测试中,有证据表明M2比M0恢复:视觉记忆,功能评估短测试(FAST),数字符号替代和立方体。在多变量分析中,年龄为55岁、辅助化疗、存在合共病、吸烟和饮酒以及GT变异rs1800795与M0和M1之间的认知能力下降有关。结论:55岁、女性、是否存在合并症、基础教育程度与化疗后认知功能障碍发生风险增高有关。
{"title":"[Risk factors for cancer-related cognitive impairment in breast and colorectal cancer patients who undergo chemotherapy].","authors":"Patricia Iranzo,&nbsp;Ana Callejo,&nbsp;Julio Arbej,&nbsp;Sebastian Menao,&nbsp;Dolores Isla,&nbsp;Raquel Andrés","doi":"10.23938/ASSN.1040","DOIUrl":"https://doi.org/10.23938/ASSN.1040","url":null,"abstract":"<p><strong>Background: </strong>Our study aims to evaluate the impact of different factors on cancer-related cognitive impairment in patients who undergo chemotherapy.</p><p><strong>Methodology: </strong>Prospective longitudinal single-centre study that included patients with breast and colon carcinoma who underwent chemotherapy as part of their treatment. Clinical and genetic characteristics of the patients (single nucleotide polymorphisms, SNPs) were collected. Patients' neurocognitive status was assessed using eleven validated tests at three time points: before chemotherapy (M0 - baseline), between one and four weeks after completing chemotherapy (M1), and between 24-30 weeks after completing chemotherapy (M2).</p><p><strong>Results: </strong>Sixty-two patients were included in this study; 82% were female, median age was 56 years (range 30-74), and 64.5% had been diagnosed with breast cancer. Overall, better cognitive results at M0 were associated with age < 55 years, higher educational level, absence of comorbidities, and the CC variant rs471692 (TOP2A). Significant decline was found between M0 to M1 in the Rey Auditory Verbal Learning Test and the Letter and Number test, with evidence of recovery in M2 compared to M0 regarding the following test: Visual Memory, Functioning Assessment Short Test (FAST), Digit Symbol Substitution and Cube. In the multivariate analysis, being =55 years of age, adjuvant chemotherapy, presence of comorbidities, tobacco and alcohol use, and GT variant rs1800795 were associated with cognitive decline between M0 and M1.</p><p><strong>Conclusion: </strong>Being =55 years of age, female, presence of comorbidities and basic education level are related to a higher risk of cognitive impairment after chemotherapy.</p>","PeriodicalId":7775,"journal":{"name":"Anales Del Sistema Sanitario De Navarra","volume":"46 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a8/7a/assn-46-02-e1040.PMC10498134.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10603733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Translation and transcultural adaptation of the Person-Centred Practice Inventory Staff (PCPI-S) for health professionals in Spain]. [针对西班牙卫生专业人员的以人为本的实践清单人员(PCPI-S)的翻译和跨文化改编]。
IF 1 4区 医学 Q3 Medicine Pub Date : 2023-08-16 DOI: 10.23938/ASSN.1039
Begoña Errasti-Ibarrondo, Virginia La Rosa-Salas, Marta Lizarbe-Chocarro, Yvonne Gavela-Ramos, Ana Choperena, Leire Arbea Moreno, Mónica Vázquez-Calatayud, María José Galán-Espinilla, Brendan McCormack, Ana Carvajal-Valcárcel

Background: Person-centred practices - following national and international developments in health-care policies - have become a key approach in healthcare. The Person-Centred Practice Inventory - Staff is an instrument based on the theoretical framework Person-Centred Practice that focuses on the staff's perspective and how they experience person-centred practices. Here, the aim of this study is to obtain the first Spanish version of the PCPI-S translated and adapted into the Spanish context.

Methods: The translation and adaptation of the instrument followed the Translation and Cultural Adaptation of Patient Reported Outcomes Measures - Principles of Good Practice, which included a consulting session with experts. Content validation measures on clarity and relevance were assessed for every item (I-CVI) and the survey as a whole (S-CVI/Ave).

Results: No major difficulties were registered to reach an agreement on the 12 items that needed to be clarified. Regarding clarity and relevance. The validity index per item (I-CVI) obtained excellent scores for clarity in 53 items and for relevance in 59; the S-CVI/Ave showed excellent results (=90).

Conclusions: This first version of the Person-Centred Practice Inventory - Staff instrument adapted to the Spanish context is conceptually and semantically equivalent to the original one. This valuable tool will be of great help to identify the perception of healthcare professionals on person-centred practices.

背景:随着国家和国际卫生保健政策的发展,以人为本的做法已成为卫生保健的一种关键方法。以人为本的实践清单-员工是一个基于以人为本的实践理论框架的工具,该框架侧重于员工的观点以及他们如何体验以人为本的实践。在这里,本研究的目的是获得第一个西班牙语版本的PCPI-S翻译并适应西班牙语语境。方法:仪器的翻译和改编遵循患者报告结果测量的翻译和文化适应-良好实践原则,其中包括与专家的咨询会议。对每个项目(I-CVI)和整个调查(S-CVI/Ave)的清晰度和相关性的内容验证措施进行评估。结果:在需要澄清的12个项目上达成一致没有重大困难。关于清晰度和相关性。每个项目的效度指数(I-CVI)在53个项目的清晰度和59个项目的相关性方面获得了优异的分数;S-CVI/Ave表现优异(=90)。结论:第一个版本的“以人为本的实践清单-工作人员工具”适应西班牙上下文,在概念和语义上与原始版本相同。这个有价值的工具将极大地帮助确定卫生保健专业人员对以人为本的做法的看法。
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Anales Del Sistema Sanitario De Navarra
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