[Solitary dorsal paravertebral tumor: radiological and histopathological characterization of a pediatric case of nodular fasciitis].

IF 1 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Anales Del Sistema Sanitario De Navarra Pub Date : 2022-12-28 DOI:10.23938/ASSN.1025
Javier Arredondo Montero, Teresa Dot Gómara, Sara Hernández-Martín, Mónica Bronte Anaut, Marta Montes
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Abstract

Nodular fasciitis is a benign soft tissue lesion with rapid fibroblastic or myofibroblastic proliferation, rarely observed in pediatric patients. Here, we present the case of a seven-year-old boy with no relevant medical records, in whom an asymptomatic dorsal tumor was incidentally identified. Magnetic resonance imaging showed a left dorsal paravertebral lesion with hypointensity on T1, hyperintensity on T2, peripheral contrast enhancement, and the so-called fascial tail sign. Complete surgical resection of the lesion was achieved. The histopathological study showed a proliferation of spindle or stellate cells with nuclei without atypia in a myxoid or collagenized stroma. The immunohistochemical profile showed positivity for smooth muscle actin, muscle-specific actin antibody HHF35, and calponin. The lesion was diagnosed as nodular fasciitis, an entity with broad and complex differential diagnosis. Presence of specific radiological signs and adequate immunohistochemical characterization of the lesion help perform an accurate diagnosis.

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[孤立背椎旁肿瘤:1例小儿结节性筋膜炎的影像学和组织病理学特征]。
结节性筋膜炎是一种良性软组织病变,伴成纤维细胞或肌成纤维细胞快速增生,在儿科患者中很少观察到。在这里,我们提出一个没有相关医疗记录的七岁男孩的病例,其中一个无症状的背部肿瘤被偶然发现。磁共振成像显示左背椎旁病变,T1低,T2高,周围增强,所谓的筋膜尾征。手术完全切除病变。组织病理学研究显示,在黏液样或胶原基质中,无异型性的梭形或星状细胞核增生。免疫组化分析显示平滑肌肌动蛋白、肌肉特异性肌动蛋白抗体HHF35和钙钙蛋白阳性。病变被诊断为结节性筋膜炎,一个具有广泛和复杂鉴别诊断的实体。特异的放射学征象和充分的病变免疫组织化学特征有助于进行准确的诊断。
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来源期刊
Anales Del Sistema Sanitario De Navarra
Anales Del Sistema Sanitario De Navarra 医学-公共卫生、环境卫生与职业卫生
CiteScore
1.30
自引率
30.00%
发文量
88
审稿时长
>12 weeks
期刊介绍: La revista Anales del Sistema Sanitario de Navarra es una revista de contenido médico sanitario de carácter generalista. En ella tienen cabida artículos referidos a temas de salud/enfermedad en general, salud pública, administración y gestión sanitaria y Atención Primaria de salud.
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