Electroceuticals for Neurogastroenterology and Motility Disorders.

Yan Jiang, Edy Soffer
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Abstract

Purpose of review: To provide an updated overview on use of electrostimulation in gastrointestinal motility disorders and obesity, with a focus on gastric electrical stimulation, vagal nerve stimulation and sacral nerve stimulation.

Recent findings: Recent studies on gastric electrical stimulation for chronic vomiting showed a decrease in frequency of vomiting, but without significant improvement in quality of life. Percutaneous vagal nerve stimulation shows some promise for both symptoms of gastroparesis and IBS. Sacral nerve stimulation does not appear effective for constipation. Studies of electroceuticals for treatment of obesity have quite varied results with less clinical penetrance of the technology. Results of studies on the efficacy of electroceuticals have been variable depending on pathology but this area remains promising. Improved mechanistic understanding, technology and more controlled trials will be helpful to establish a clearer role for electrostimulation in treatment of various GI disorders.

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神经胃肠病学和运动障碍的电疗法。
综述目的:综述电刺激治疗胃肠运动障碍和肥胖的最新进展,重点是胃电刺激、迷走神经刺激和骶神经刺激。近期发现:近期研究表明,胃电刺激治疗慢性呕吐可减少呕吐频率,但对生活质量无显著改善。经皮迷走神经刺激对胃轻瘫和肠易激综合征都有一定的疗效。骶神经刺激似乎对便秘无效。电子药物治疗肥胖的研究结果各不相同,但该技术的临床外显率较低。关于电药疗效的研究结果因病理而异,但这一领域仍有希望。提高对电刺激机制的理解、技术和更多的对照试验将有助于明确电刺激在治疗各种胃肠道疾病中的作用。
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来源期刊
Current Gastroenterology Reports
Current Gastroenterology Reports Medicine-Gastroenterology
CiteScore
7.80
自引率
0.00%
发文量
19
期刊介绍: As the field of gastroenterology and hepatology rapidly evolves, the wealth of published literature can be overwhelming. The aim of the journal is to help readers stay abreast of such advances by offering authoritative, systematic reviews by leading experts. We accomplish this aim by appointing Section Editors who invite international experts to contribute review articles that highlight recent developments and important papers published in the past year. Major topics in gastroenterology are covered, including pediatric gastroenterology, neuromuscular disorders, infections, nutrition, and inflammatory bowel disease. These reviews provide clear, insightful summaries of expert perspectives relevant to clinical practice. An Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research. We also provide commentaries from well-known figures in the field.
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