Real-life effectiveness and safety of dupilumab in adolescents with atopic dermatitis: a 52-week single-center retrospective study.

IF 2.9 4区 医学 Q2 DERMATOLOGY Journal of Dermatological Treatment Pub Date : 2023-04-06 DOI:10.1080/09546634.2023.2200867
Luigi Gargiulo, Carlo Alberto Vignoli, Luciano Ibba, Andrea Cortese, Mario Valenti, Antonio Costanzo, Alessandra Narcisi
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引用次数: 1

Abstract

Dupilumab is a monoclonal antibody that selectively targets the alpha subunit of the interleukin-4-Receptor and it is approved for the treatment of atopic dermatitis in adults, children and adolescents. Real life data on effectiveness and safety of dupilumab in adolescents are limited.In this study, 30 patients who started dupilumab between the ages of 12 and 18 were evaluated. All patients completed at least 16 weeks of therapy, with 25 reaching week 52. In our experience, the mean Eczema Area and Severity Index decreased from 23.25 ± 4.15 at baseline to 2.06 ± 1.99 at week 52.
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dupilumab治疗青少年特应性皮炎的有效性和安全性:一项52周的单中心回顾性研究
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来源期刊
CiteScore
6.50
自引率
0.00%
发文量
145
审稿时长
6-12 weeks
期刊介绍: The Journal of Dermatological Treatment covers all aspects of the treatment of skin disease, including the use of topical and systematically administered drugs and other forms of therapy. The Journal of Dermatological Treatment is positioned to give dermatologists cutting edge information on new treatments in all areas of dermatology. It also publishes valuable clinical reviews and theoretical papers on dermatological treatments.
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