Diuretics in Different Samples: Update on the Pretreatment and Analysis Techniques.

IF 4.2 2区 化学 Q1 CHEMISTRY, ANALYTICAL Critical reviews in analytical chemistry Pub Date : 2024-01-01 Epub Date: 2023-05-02 DOI:10.1080/10408347.2023.2202260
Ya-Jie Liu, Yu Bian, Yuan Zhang, Yi-Xin Zhang, Ai Ren, Shu-Han Lin, Xue-Song Feng, Xin-Yuan Zhang
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Abstract

Diuretics are drugs that promote the excretion of water and electrolytes in the body and produce diuretic effects. Clinically, they are often used in the treatment of edema caused by various reasons and hypertension. In sports, diuretics are banned by the World Anti-Doping Agency (WADA). Therefore, in order to monitor blood drug concentration, identify drug quality and maintain the fairness of sports competition, accurate, rapid, highly selective and sensitive detection methods are essential. This review provides a comprehensive summary of the pretreatment and detection of diuretics in various samples since 2015. Commonly used techniques to extract diuretics include liquid-liquid extraction, liquid-phase microextraction, solid-phase extraction, solid-phase microextraction, among others. Determination methods include methods based on liquid chromatography, fluorescent spectroscopy, electrochemical sensor method, capillary electrophoresis and so on. The advantages and disadvantages of various pretreatment and analytical techniques are elaborated. In addition, future development prospects of these techniques are discussed.

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不同样本中的利尿剂:前处理和分析技术的最新进展。
利尿剂是促进体内水分和电解质排泄并产生利尿作用的药物。在临床上,它们常用于治疗各种原因引起的水肿和高血压。在体育运动中,利尿剂被世界反兴奋剂机构(WADA)禁用。因此,为了监测血液中的药物浓度、鉴别药物质量和维护体育竞赛的公平性,准确、快速、高选择性和高灵敏度的检测方法是必不可少的。本综述全面总结了 2015 年以来各种样本中利尿剂的前处理和检测情况。常用的利尿剂提取技术包括液液萃取、液相微萃取、固相萃取、固相微萃取等。测定方法包括液相色谱法、荧光光谱法、电化学传感器法、毛细管电泳法等。此外,还阐述了各种预处理和分析技术的优缺点。此外,还讨论了这些技术的未来发展前景。
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来源期刊
CiteScore
12.00
自引率
4.00%
发文量
137
审稿时长
6 months
期刊介绍: Critical Reviews in Analytical Chemistry continues to be a dependable resource for both the expert and the student by providing in-depth, scholarly, insightful reviews of important topics within the discipline of analytical chemistry and related measurement sciences. The journal exclusively publishes review articles that illuminate the underlying science, that evaluate the field''s status by putting recent developments into proper perspective and context, and that speculate on possible future developments. A limited number of articles are of a "tutorial" format written by experts for scientists seeking introduction or clarification in a new area. This journal serves as a forum for linking various underlying components in broad and interdisciplinary means, while maintaining balance between applied and fundamental research. Topics we are interested in receiving reviews on are the following: · chemical analysis; · instrumentation; · chemometrics; · analytical biochemistry; · medicinal analysis; · forensics; · environmental sciences; · applied physics; · and material science.
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