Effect of Carbodiimide (EDC) on the Bond Strength Longevity of Epoxy Resin-based Endodontic Sealer to Root Dentin: An In-Vitro Study.

IF 2.5 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Journal of Adhesive Dentistry Pub Date : 2023-05-16 DOI:10.3290/j.jad.b4097187

Pedro Henrique Bernardes Caetano, Helena Cristina de Assis, Leonardo Moreira Teodosio, Gunther Ricardo Bertolini, Renato Roperto, Manoel Damião Sousa-Neto, Fabiane Carneiro Lopes-Olhê

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Abstract

Purpose: EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride) can increase dentin bonding longevity. This study aimed to evaluate the effect of final irrigation of the root canal with EDC on the bond strength (BS) longevity of an epoxy resin-based root-canal sealer.

Materials and methods: Twenty maxillary canines were sectioned and standardized for root length at 17 mm. Roots were instrumented and distributed into 2 groups according to the final irrigation protocol: EDTA 17%+NaOCl 2.5% (C) and EDTA 17%+NaOCl 2.5%+EDC 0.5M (EDC). The canals were dried and filled with AH Plus (Dentsply Sirona). Three slices were obtained per third, and the first slice from each third was used for the immediate push-out test (i) followed by analysis of the failure pattern (n = 10); the second slice from each third was used for the push-out test after 6-month aging (A) followed by analysis of the failure pattern (n = 10); the third slice from each third was used to examine the adhesive interface under confocal laser scanning microscopy (CLSM) (n = 10). Data were analyzed with ANOVA, Fisher's exact and Kruskal-Wallis tests.

Results: Higher BSs were found for EDC-A (5.6 ± 1.9) than for EDC-I (3.3 ± 0.7), C-i (2.5 ± 1.0) and C-i (2.6 ± 1.0) (p = 0.0001), while C-A values were in some cases similar to C-i and in others similar to EDC-i. No statistically significant difference was observed between the thirds (p > 0.05), except for EDC-i, which showed lower BS for the cervical (2.79 ± 0.46) compared to the apical third (3.8 ± 0.5), while the middle third in some cases had values similar to those of the apical and in others to the cervical third (3.2 ± 0.7) (p = 0.032). More mixed adhesive failures were found in the cervical third, and more adhesive failures to the sealer occurred in the middle and apical thirds (p = 0.014). A significant difference was observed between treatments in terms of adaptation of the adhesive interface, with a higher percentage of good adaptation using EDC (66.7%) than using C (40%), and a lower percentage of poor adaptation with EDC (10%) compared to C (20%) (p < 0.05).

Conclusion: Root canal irrigation with EDC increased the longevity of the adhesive interface of an epoxy resin-based root-canal sealer.

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碳化二亚胺 (EDC) 对环氧树脂类牙髓封闭剂与牙根牙本质粘接强度寿命的影响：体外研究

目的：EDC（1-乙基-3-（3-二甲胺基丙基）碳二亚胺盐酸盐）可以延长牙本质粘接寿命。本研究旨在评估用 EDC 对根管进行最终灌洗对环氧树脂基根管封闭剂粘接强度（BS）寿命的影响：对 20 颗上颌犬齿进行切片，并将根长标准化为 17 毫米。对牙根进行器械操作，并根据最终灌洗方案将其分为两组：EDTA 17%+NaOCl 2.5% (C) 和 EDTA 17%+NaOCl 2.5%+EDC 0.5M (EDC)。牙槽干燥后填充 AH Plus（Dentsply Sirona）。每三分之一取三片，每三分之一的第一片用于立即推出试验（i），然后分析失效模式（n = 10）；每三分之一的第二片用于老化 6 个月后的推出试验（A），然后分析失效模式（n = 10）；每三分之一的第三片用于在共聚焦激光扫描显微镜（CLSM）下检查粘接界面（n = 10）。数据分析采用方差分析、费雪精确检验和 Kruskal-Wallis 检验：发现 EDC-A 的 BS 值（5.6 ± 1.9）高于 EDC-I（3.3 ± 0.7）、C-i（2.5 ± 1.0）和 C-i（2.6 ± 1.0）（p = 0.0001），而 C-A 值在某些情况下与 C-i 相似，在另一些情况下与 EDC-i 相似。除 EDC-i 外，三分之二之间没有发现明显的统计学差异（p > 0.05），颈部的 BS 值（2.79 ± 0.46）低于顶端的三分之一（3.8 ± 0.5），而中间的三分之一在某些情况下与顶端的值相似，在另一些情况下与颈部的三分之一相似（3.2 ± 0.7）（p = 0.032）。在颈部三分之一处发现了更多的混合粘接失败，而在中部和根尖三分之一处发现了更多的封闭剂粘接失败（p = 0.014）。在粘接界面的适应性方面，不同治疗方法之间存在明显差异，使用 EDC 的适应性良好比例（66.7%）高于使用 C 的比例（40%），而使用 EDC 的适应性不良比例（10%）低于使用 C 的比例（20%）（p < 0.05）：结论：使用 EDC 进行根管灌洗可延长环氧树脂根管封闭剂粘接界面的寿命。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Adhesive Dentistry 医学-牙科与口腔外科

CiteScore

5.20

自引率

6.10%

发文量

审稿时长

6-12 weeks

期刊介绍： New materials and applications for adhesion are profoundly changing the way dentistry is delivered. Bonding techniques, which have long been restricted to the tooth hard tissues, enamel, and dentin, have obvious applications in operative and preventive dentistry, as well as in esthetic and pediatric dentistry, prosthodontics, and orthodontics. The current development of adhesive techniques for soft tissues and slow-releasing agents will expand applications to include periodontics and oral surgery. Scientifically sound, peer-reviewed articles explore the latest innovations in these emerging fields.