Factors affecting women's participation in cardiovascular research: a scoping review.

IF 2.9 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS European Journal of Cardiovascular Nursing Pub Date : 2024-03-12 DOI:10.1093/eurjcn/zvad048
Stacey Matthews, Samantha Cook, Tim Clayton, Sarah Murray, Rochelle Wynne, Julie Sanders
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Abstract

Aims: Women are underrepresented in cardiovascular trials. We sought to explore the proportional representation of women in contemporary cardiovascular research and the factors (barriers and enablers) that affect their participation in cardiovascular studies.

Methods and results: Multiple electronic databases were searched between January 2011 and September 2021 to identify papers that defined underrepresentation of women in cardiovascular research and/or reported sex-based differences in participating in cardiovascular research and/or barriers for women to participate in cardiovascular research. Data extraction was undertaken independently by two authors using a standardised data collection form. Results were summarised using descriptive statistics and narrative synthesis as appropriate.From 548 identified papers, 10 papers were included. Of those, four were conducted prospectively and six were retrospective studies. Five of the retrospective studies involved secondary analysis of trial data including over 780 trials in over 1.1 million participants. Overall, women were reported to be underrepresented in heart failure, coronary disease, myocardial infarction, and arrhythmia trials, compared to men. Barriers to participation included lack of information and understanding of the research, trial-related procedures, the perceived health status of the participant, and patient-specific factors including travel, childcare availability, and cost. A significantly higher likelihood of research participation was reported by women following a patient educational intervention.

Conclusion: This review has highlighted the underrepresentation of women in a range of cardiovascular trials. Several barriers to women's participation in cardiovascular studies were identified. Researchers could mitigate against these in future trial planning and delivery to increase women's participation in cardiovascular research.

Registration: The protocol was published on the public Open Science Framework platform on 13th August 2021 (no registration reference provided) and can be accessed at https://osf.io/ny4fd/.

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影响女性参与心血管研究的因素:范围界定综述。
目的:妇女在心血管试验中的代表性不足。我们试图探究女性在当代心血管研究中的比例以及影响她们参与心血管研究的因素(障碍和促进因素):在 2011 年 1 月至 2021 年 9 月期间,对多个电子数据库进行了检索,以确定哪些论文定义了女性在心血管研究中的代表性不足和/或报告了参与心血管研究的性别差异和/或女性参与心血管研究的障碍。数据提取由两位作者使用标准化数据收集表独立完成。在 548 篇已确定的论文中,有 10 篇论文被收录。其中,4 篇为前瞻性研究,6 篇为回顾性研究。其中五项回顾性研究涉及对试验数据的二次分析,包括 780 多项试验,参与人数超过 110 万。总体而言,与男性相比,女性在心力衰竭、冠心病、心肌梗死和心律失常试验中的代表性不足。参与试验的障碍包括缺乏信息和对研究的了解、试验相关程序、参与者认为的健康状况以及患者的具体因素,包括旅行、能否照顾孩子和费用。据报告,妇女在接受患者教育干预后参与研究的可能性明显增加:本综述强调了一系列心血管试验中女性参与人数不足的问题。研究发现了女性参与心血管研究的几个障碍。研究人员可以在未来的试验规划和实施中减少这些障碍,从而提高女性在心血管研究中的参与度:该协议已于 2021 年 8 月 13 日在公共开放科学框架平台上发布(未提供注册编号),可通过 https://osf.io/ny4fd/ 访问。
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来源期刊
European Journal of Cardiovascular Nursing
European Journal of Cardiovascular Nursing CARDIAC & CARDIOVASCULAR SYSTEMS-NURSING
CiteScore
5.10
自引率
10.30%
发文量
247
审稿时长
6-12 weeks
期刊介绍: The peer-reviewed journal of the European Society of Cardiology’s Council on Cardiovascular Nursing and Allied Professions (CCNAP) covering the broad field of cardiovascular nursing including chronic and acute care, cardiac rehabilitation, primary and secondary prevention, heart failure, acute coronary syndromes, interventional cardiology, cardiac care, and vascular nursing.
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