A nonparametric instrumental approach to confounding in competing risks models.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2023-10-01 Epub Date: 2023-05-09 DOI:10.1007/s10985-023-09599-3
Jad Beyhum, Jean-Pierre Florens, Ingrid Van Keilegom
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Abstract

This paper discusses nonparametric identification and estimation of the causal effect of a treatment in the presence of confounding, competing risks and random right-censoring. Our identification strategy is based on an instrumental variable. We show that the competing risks model generates a nonparametric quantile instrumental regression problem. Quantile treatment effects on the subdistribution function can be recovered from the regression function. A distinguishing feature of the model is that censoring and competing risks prevent identification at some quantiles. We characterize the set of quantiles for which exact identification is possible and give partial identification results for other quantiles. We outline an estimation procedure and discuss its properties. The finite sample performance of the estimator is evaluated through simulations. We apply the proposed method to the Health Insurance Plan of Greater New York experiment.

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竞争风险模型中混淆的非参数工具方法。
本文讨论了在存在混杂、竞争风险和随机权利审查的情况下,治疗因果效应的非参数识别和估计。我们的识别策略基于一个工具变量。我们证明了竞争风险模型产生了一个非参数分位数工具回归问题。可以从回归函数中恢复对次分布函数的量化处理效果。该模型的一个显著特征是,审查和竞争风险阻止了某些分位数的识别。我们刻画了可能进行精确识别的分位数集,并给出了其他分位数的部分识别结果。我们概述了一个估计过程,并讨论了它的性质。通过仿真评估了估计器的有限样本性能。我们将所提出的方法应用于大纽约地区的健康保险计划实验。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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