Management of non-alcoholic fatty liver disease incidentally detected during other medical assessments.

Q2 Pharmacology, Toxicology and Pharmaceutics Drugs in Context Pub Date : 2023-05-11 eCollection Date: 2023-01-01 DOI:10.7573/dic.2023-1-3
Yeong Yeh Lee, Vincent Tee
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Abstract

Elevated liver enzyme levels are a frequent incidental finding in primary care, and non-alcoholic fatty liver disease is the main cause of incidental elevation of liver enzymes worldwide. The features of the disease vary from simple steatosis, characterized by a benign prognosis, to non-alcoholic steatohepatitis and cirrhosis, increasing morbidity and mortality. In this case report, abnormal liver activity was incidentally detected during other medical assessments. The patient was treated with silymarin 140 mg three times daily, resulting in decreased serum liver enzyme levels over treatment with a good safety profile. This article is part of the Current clinical use of silymarin in the treatment of toxic liver diseases: a case series Special Issue: https://www.drugsincontext.com/special_issues/current-clinical-use-of-silymarin-in-the-treatment-of-toxic-liver-diseases-a-case-series.

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管理在其他医疗评估中偶然发现的非酒精性脂肪肝。
肝酶水平升高是初级保健中经常出现的偶然发现,而非酒精性脂肪肝是全球肝酶偶然升高的主要原因。该病的特征各不相同,从以良性预后为特征的单纯脂肪变性,到增加发病率和死亡率的非酒精性脂肪性肝炎和肝硬化。在本病例报告中,肝脏活动异常是在其他医疗评估中偶然发现的。患者接受了水飞蓟素 140 毫克、每日三次的治疗,结果治疗期间血清肝酶水平下降,安全性良好。本文是《水飞蓟素在治疗中毒性肝病中的临床应用:病例系列》特刊的一部分:https://www.drugsincontext.com/special_issues/current-clinical-use-of-silymarin-in-the-treatment-of-toxic-liver-diseases-a-case-series。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Drugs in Context
Drugs in Context Medicine-Medicine (all)
CiteScore
5.90
自引率
0.00%
发文量
63
审稿时长
9 weeks
期刊介绍: Covers all phases of original research: laboratory, animal and human/clinical studies, health economics and outcomes research, and postmarketing studies. Original research that shows positive or negative results are welcomed. Invited review articles may cover single-drug reviews, drug class reviews, latest advances in drug therapy, therapeutic-area reviews, place-in-therapy reviews, new pathways and classes of drugs. In addition, systematic reviews and meta-analyses are welcomed and may be published as original research if performed per accepted guidelines. Editorials of key topics and issues in drugs and therapeutics are welcomed. The Editor-in-Chief will also consider manuscripts of interest in areas such as technologies that support diagnosis, assessment and treatment. EQUATOR Network reporting guidelines should be followed for each article type. GPP3 Guidelines should be followed for any industry-sponsored manuscripts. Other Editorial sections may include Editorial, Case Report, Conference Report, Letter-to-the-Editor, Educational Section.
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