{"title":"Recent Advances in Imported Malaria Pathogenesis, Diagnosis, and Management.","authors":"Anastasia S Weiland","doi":"10.1007/s40138-023-00264-5","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose of review: </strong>Malaria is an important human parasitic disease affecting the population of tropical, subtropical regions as well as travelers to these areas.The purpose of this article is to provide clinicians practicing in non-endemic areas with a comprehensive overview of the recent data on microbiologic and pathophysiologic features of five <i>Plasmodium</i> parasites, clinical presentation of uncomplicated and severe cases, modern diagnostic methods, and treatment of malaria.</p><p><strong>Recent findings: </strong>Employment of robust surveillance programs, rapid diagnostic tests, highly active artemisinin-based therapy, and the first malaria vaccine have led to decline in malaria incidence; however, emerging drug resistance, disruptions due to the COVID-19 pandemic, and other socio-economic factors have stalled the progress.</p><p><strong>Summary: </strong>Clinicians practicing in non-endemic areas such as the United States should consider a diagnosis of malaria in returning travelers presenting with fever, utilize rapid diagnostic tests if available at their practice locations in addition to microscopy, and timely initiate guideline-directed management as delays in treatment can lead to poor clinical outcomes.</p>","PeriodicalId":43451,"journal":{"name":"Current Emergency and Hospital Medicine Reports","volume":"11 2","pages":"49-57"},"PeriodicalIF":1.4000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091340/pdf/","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Emergency and Hospital Medicine Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s40138-023-00264-5","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"EMERGENCY MEDICINE","Score":null,"Total":0}
引用次数: 1
Abstract
Purpose of review: Malaria is an important human parasitic disease affecting the population of tropical, subtropical regions as well as travelers to these areas.The purpose of this article is to provide clinicians practicing in non-endemic areas with a comprehensive overview of the recent data on microbiologic and pathophysiologic features of five Plasmodium parasites, clinical presentation of uncomplicated and severe cases, modern diagnostic methods, and treatment of malaria.
Recent findings: Employment of robust surveillance programs, rapid diagnostic tests, highly active artemisinin-based therapy, and the first malaria vaccine have led to decline in malaria incidence; however, emerging drug resistance, disruptions due to the COVID-19 pandemic, and other socio-economic factors have stalled the progress.
Summary: Clinicians practicing in non-endemic areas such as the United States should consider a diagnosis of malaria in returning travelers presenting with fever, utilize rapid diagnostic tests if available at their practice locations in addition to microscopy, and timely initiate guideline-directed management as delays in treatment can lead to poor clinical outcomes.
期刊介绍：
This journal aims to offer expert review articles on the most significant recent developments in emergency and hospital medicine, with particular emphasis on the transition of patient care from the emergency department to the hospitalist service. By providing clear, insightful, balanced contributions, the journal intends to serve 1) those who provide immediate medical attention to patients with acute injuries or conditions in emergency departments and emergency medical service settings, and 2) hospitalists who deliver comprehensive medical care in collaboration with physicians and other health care personnel responsible for hospitalized patients. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas across the field. Section Editors select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An Editorial Board of more than 20 internationally diverse members reviews the annual table of contents, ensures that topics include emerging research, and suggests topics of special importance to their country/region. Topics covered may include acute coronary syndrome; chronic obstructive pulmonary disease; community-acquired infections; diabetes and metabolic disease; heart failure; hospital-acquired infections; pharmacology of acute care; shared practice and economic issues; and thrombosis.
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