Craniofacial Fibrous Dysplasia: Clinical and Therapeutic Implications.

IF 4.2 2区医学 Q1 ENDOCRINOLOGY & METABOLISM Current Osteoporosis Reports Pub Date : 2023-04-01 Epub Date: 2023-02-28 DOI:10.1007/s11914-023-00779-6

Vivian Szymczuk, Jocelyn Taylor, Alison M Boyce

引用次数: 0

Abstract

Purpose of review: This study aims to review diagnosis, potential complications, and clinical management in craniofacial fibrous dysplasia.

Recent findings: Fibrous dysplasia (FD) is a rare mosaic disorder in which normal bone and marrow are replaced with expansile fibro-osseous lesions. Disease presents along a broad spectrum and may be associated with extraskeletal features as part of McCune-Albright syndrome (MAS). The craniofacial skeleton is one of the most commonly impacted areas in FD, and its functional and anatomical complexities create unique challenges for diagnosis and management. This review summarizes current approaches to diagnosis and management in FD/MAS, with emphasis on the clinical and therapeutic implications for the craniofacial skeleton.

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颅面纤维性发育不良：临床和治疗意义。

综述目的：本研究旨在回顾颅面纤维发育不良的诊断、潜在并发症和临床治疗：纤维发育不良（FD）是一种罕见的镶嵌性疾病，正常骨骼和骨髓被扩张性纤维骨病变所取代。该病的表现范围很广，可能与骨骼外特征相关，是麦库纳-阿尔布莱特综合征（McCune-Albright Syndrome，MAS）的一部分。颅面骨骼是 FD 最常受影响的部位之一，其功能和解剖上的复杂性给诊断和管理带来了独特的挑战。本综述总结了目前诊断和治疗 FD/MAS 的方法，重点是颅面骨骼的临床和治疗意义。

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来源期刊

Current Osteoporosis Reports Medicine-Endocrinology, Diabetes and Metabolism

CiteScore

8.80

自引率

2.30%

发文量

期刊介绍： This journal intends to provide clear, insightful, balanced contributions by international experts that review the most important, recently published clinical findings related to the diagnosis, treatment, management, and prevention of osteoporosis. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as current and future therapeutics, epidemiology and pathophysiology, and evaluation and management. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.