Stationary distribution and density function analysis of SVIS epidemic model with saturated incidence and vaccination under stochastic environments.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2023-06-01 DOI:10.1007/s12064-023-00392-2
Prasenjit Mahato, Sanat Kumar Mahato, Subhashis Das, Partha Karmakar
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Abstract

In this article, we study the dynamical properties of susceptible-vaccinated-infected-susceptible (SVIS) epidemic system with saturated incidence rate and vaccination strategies. By constructing the suitable Lyapunov function, we examine the existence and uniqueness of the stochastic system. With the help of Khas'minskii theory, we set up a critical value [Formula: see text] with respect to the basic reproduction number [Formula: see text] of the deterministic system. A unique ergodic stationary distribution is investigated under the condition of [Formula: see text]. In the epidemiological study, the ergodic stationary distribution represents that the disease will persist for long-term behavior. We focus for developing the general three-dimensional Fokker-Planck equation using appropriate solving theories. Around the quasi-endemic equilibrium, the probability density function of the stochastic system is analyzed which is the main theme of our study. Under [Formula: see text], both the existence of ergodic stationary distribution and density function can elicit all the dynamical behavior of the disease persistence. The condition of disease extinction of the system is derived. For supporting theoretical study, we discuss the numerical results and the sensitivities of the biological parameters. Results and conclusions are highlighted.

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随机环境下具有饱和发病率和疫苗接种的SVIS流行模型的平稳分布和密度函数分析。
本文研究了具有饱和发病率的易感-接种-感染-易感(SVIS)流行病系统的动力学性质和疫苗接种策略。通过构造合适的Lyapunov函数,研究了随机系统的存在唯一性。借助于Khas’minskii理论,我们对确定性系统的基本再生产数[公式:见文]建立了一个临界值[公式:见文]。在[公式:见文]的条件下,研究了一个唯一的遍历平稳分布。在流行病学研究中,遍历平稳分布表示该疾病将持续存在长期行为。我们的重点是利用适当的求解理论建立一般的三维福克-普朗克方程。围绕准地方性平衡,分析了随机系统的概率密度函数,这是我们研究的主题。在[公式:见文]下,遍历平稳分布和密度函数的存在都可以引出疾病持续的所有动力学行为。导出了系统的疾病消除条件。为了支持理论研究,我们讨论了数值结果和生物参数的灵敏度。突出显示结果和结论。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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