Sleep Disruption and Bone Health.

IF 4.2 2区医学 Q1 ENDOCRINOLOGY & METABOLISM Current Osteoporosis Reports Pub Date : 2022-06-01 DOI:10.1007/s11914-022-00733-y

Christine Swanson

{"title":"Sleep Disruption and Bone Health.","authors":"Christine Swanson","doi":"10.1007/s11914-022-00733-y","DOIUrl":null,"url":null,"abstract":"Purpose of review: Review recent literature investigating the relationship between bone health and sleep/circadian disruptions (e.g., abnormal sleep duration, night shift work).Recent findings: Short and long sleep are associated with low bone mineral density (BMD). Recent data from observational studies identified an increased risk of fracture in women with short sleep. Studies suggest that age, sex, weight change, and concurrent circadian misalignment may modify the effects of sleep restriction on bone metabolism. Interventional studies demonstrate alterations in bone metabolism and structure in response to circadian disruption that could underlie the increased fracture risk seen with night shift work. The effects of sleep and circadian disruption during adolescence may have lifelong skeletal consequences if they adversely impact bone modeling. Data suggest that short sleep and night shift work negatively impact bone metabolism and health. Rigorous studies of prevalent sleep and circadian disruptions are needed to determine mechanisms and develop prevention strategies to optimize lifelong skeletal health.","PeriodicalId":11080,"journal":{"name":"Current Osteoporosis Reports","volume":"20 3","pages":"202-212"},"PeriodicalIF":4.2000,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108658/pdf/nihms-1884694.pdf","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Osteoporosis Reports","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s11914-022-00733-y","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}

引用次数: 3

Abstract

Purpose of review: Review recent literature investigating the relationship between bone health and sleep/circadian disruptions (e.g., abnormal sleep duration, night shift work).

Recent findings: Short and long sleep are associated with low bone mineral density (BMD). Recent data from observational studies identified an increased risk of fracture in women with short sleep. Studies suggest that age, sex, weight change, and concurrent circadian misalignment may modify the effects of sleep restriction on bone metabolism. Interventional studies demonstrate alterations in bone metabolism and structure in response to circadian disruption that could underlie the increased fracture risk seen with night shift work. The effects of sleep and circadian disruption during adolescence may have lifelong skeletal consequences if they adversely impact bone modeling. Data suggest that short sleep and night shift work negatively impact bone metabolism and health. Rigorous studies of prevalent sleep and circadian disruptions are needed to determine mechanisms and develop prevention strategies to optimize lifelong skeletal health.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

睡眠中断和骨骼健康。

综述目的:综述近期研究骨骼健康与睡眠/昼夜节律中断(如异常睡眠时间、夜班工作)之间关系的文献。最近的研究发现:短睡眠和长睡眠与低骨密度(BMD)有关。观察性研究的最新数据表明，睡眠不足的女性骨折的风险增加。研究表明，年龄、性别、体重变化和同步的昼夜节律失调可能会改变睡眠限制对骨代谢的影响。干预性研究表明，由于昼夜节律紊乱，骨代谢和结构发生了改变，这可能是夜班工作中骨折风险增加的原因。如果青春期睡眠和昼夜节律紊乱对骨骼建模产生不利影响，可能会对骨骼产生终生影响。数据显示，睡眠不足和夜班工作会对骨骼代谢和健康产生负面影响。需要对普遍的睡眠和昼夜节律中断进行严格的研究，以确定机制并制定预防策略，以优化终身骨骼健康。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Current Osteoporosis Reports Medicine-Endocrinology, Diabetes and Metabolism

CiteScore

8.80

自引率

2.30%

发文量

期刊介绍： This journal intends to provide clear, insightful, balanced contributions by international experts that review the most important, recently published clinical findings related to the diagnosis, treatment, management, and prevention of osteoporosis. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as current and future therapeutics, epidemiology and pathophysiology, and evaluation and management. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.