A SiO2 Hybrid Enzyme-Based Biosensor with Enhanced Electrochemical Stability for Accuracy Detection of Glucose.

IF 1.7 4区 化学 Q3 CHEMISTRY, ANALYTICAL International Journal of Analytical Chemistry Pub Date : 2023-01-01 DOI:10.1155/2023/6620613
Li Mei, Yiting Yang, Jiagen Li, Shuyong Shang, Xiaohong Fu
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Abstract

A novel enzyme-based biosensor for glucose detection is successfully developed using layer-by-layer assembly technology. The introduction of commercially available SiO2 was found to be a facile way to improve overall electrochemical stability. After 30 CV cycles, the proposed biosensor could retain 95% of its original current. The biosensor presents good detection stability and reproducibility with the detection concentration range of 1.96 × 10-9 to 7.24 × 10-7 M. This study demonstrated that the hybridization of cheap inorganic nanoparticles was a useful method in preparing high-performance biosensors with a much lower cost.

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具有增强电化学稳定性的二氧化硅杂化酶生物传感器用于葡萄糖的精确检测。
利用逐层组装技术成功研制了一种新型的酶基葡萄糖检测生物传感器。研究发现,引入市售SiO2是提高整体电化学稳定性的一种简便方法。经过30个CV循环后,所提出的生物传感器可以保持95%的原始电流。该传感器具有良好的检测稳定性和重复性,检测浓度范围为1.96 × 10-9 ~ 7.24 × 10-7 M。该研究表明,廉价无机纳米粒子的杂交是一种制备高性能生物传感器的有效方法,而且成本低得多。
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来源期刊
CiteScore
3.10
自引率
5.60%
发文量
117
期刊介绍: International Journal of Analytical Chemistry publishes original research articles that report new experimental results and methods, especially in relation to important analytes, difficult matrices, and topical samples. Investigations may be fundamental, or else related to specific applications; examples being biological, environmental and food testing, and analysis in chemical synthesis and materials processing. As well as original research, the International Journal of Analytical Chemistry also publishes focused review articles that examine the state of the art, identify emerging trends, and suggest future directions for developing fields.
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