Deep conservation and co-option of programmed cell death facilitates evolution of alternative phenotypes at multiple biological levels

IF 6.2 2区 生物学 Q1 CELL BIOLOGY Seminars in cell & developmental biology Pub Date : 2023-08-01 DOI:10.1016/j.semcdb.2022.05.024
Lisa Hanna, Ehab Abouheif
{"title":"Deep conservation and co-option of programmed cell death facilitates evolution of alternative phenotypes at multiple biological levels","authors":"Lisa Hanna,&nbsp;Ehab Abouheif","doi":"10.1016/j.semcdb.2022.05.024","DOIUrl":null,"url":null,"abstract":"<div><p><span>Alternative phenotypes, such as polyphenisms and sexual dimorphisms, are widespread in nature and appear at all levels of biological organization, from genes and cells to morphology and behavior. Yet, our understanding of the mechanisms through which alternative phenotypes develop and how they evolve remains understudied. In this review, we explore the association between alternative phenotypes and programmed cell death, a mechanism responsible for the elimination of superfluous cells during development. We discuss the ancient origins and deep conservation of programmed cell death (its function, forms and underlying core regulatory gene networks), and propose that it was co-opted repeatedly to generate alternative phenotypes at the level of cells, tissues, organs, external morphology, and even individuals. We review several examples from across the </span>tree of life to explore the conditions under which programmed cell death is likely to facilitate the evolution of alternative phenotypes.</p></div>","PeriodicalId":21735,"journal":{"name":"Seminars in cell & developmental biology","volume":null,"pages":null},"PeriodicalIF":6.2000,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Seminars in cell & developmental biology","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1084952122001793","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CELL BIOLOGY","Score":null,"Total":0}
引用次数: 3

Abstract

Alternative phenotypes, such as polyphenisms and sexual dimorphisms, are widespread in nature and appear at all levels of biological organization, from genes and cells to morphology and behavior. Yet, our understanding of the mechanisms through which alternative phenotypes develop and how they evolve remains understudied. In this review, we explore the association between alternative phenotypes and programmed cell death, a mechanism responsible for the elimination of superfluous cells during development. We discuss the ancient origins and deep conservation of programmed cell death (its function, forms and underlying core regulatory gene networks), and propose that it was co-opted repeatedly to generate alternative phenotypes at the level of cells, tissues, organs, external morphology, and even individuals. We review several examples from across the tree of life to explore the conditions under which programmed cell death is likely to facilitate the evolution of alternative phenotypes.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
程序性细胞死亡的深度保护和共选择促进了多种生物学水平上的替代表型的进化
替代表型,如多基因和性二型,在自然界中广泛存在,并出现在生物组织的各个层面,从基因和细胞到形态和行为。然而,我们对替代表型发展的机制以及它们如何进化的理解仍然不足。在这篇综述中,我们探讨了替代表型与程序性细胞死亡之间的关系,程序性细胞死是一种负责在发育过程中消除多余细胞的机制。我们讨论了程序性细胞死亡的古老起源和深层保守性(其功能、形式和潜在的核心调控基因网络),并提出它被反复选择,以在细胞、组织、器官、外部形态甚至个体层面产生替代表型。我们回顾了生命树上的几个例子,以探索程序性细胞死亡可能促进替代表型进化的条件。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
CiteScore
15.10
自引率
1.40%
发文量
310
审稿时长
9.1 weeks
期刊介绍: Seminars in Cell and Developmental Biology is a review journal dedicated to keeping scientists informed of developments in the field of molecular cell and developmental biology, on a topic by topic basis. Each issue is thematic in approach, devoted to an important topic of interest to cell and developmental biologists, focusing on the latest advances and their specific implications. The aim of each issue is to provide a coordinated, readable, and lively review of a selected area, published rapidly to ensure currency.
期刊最新文献
Diverse genetic conflicts mediated by molecular mimicry and computational approaches to detect them Outside Front Cover Editorial Board/Publication Information From the cauldron of conflict: Endogenous gene regulation by piRNA and other modes of adaptation enabled by selfish transposable elements Outside Front Cover
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1