Changes in the Protein Profile in Staphylococcal Strains from Patients Infected with the SARS-CoV-2 Virus.

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2023-03-01 DOI:10.33073/pjm-2023-001
Tomasz Jarzembowski, Lidia Piechowicz, Marek Bronk, Anna Pałubicka, Łukasz Naumiuk
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Abstract

Staphylococcus aureus strains are particularly often isolated from patients with SARS-CoV-2 infection. The aim of the current research was to determine whether the SARS-CoV-2 virus infection affects the protein profile of S. aureus. Bacteria were isolated from the forty swabs collected from the patients in the hospitals of the Pomeranian region. MALDI-TOF MS spectra were obtained using a Microflex LT instrument. Twenty-nine peaks were identified. The peak (2,430) is described here for the first time and was unique for the isolates from patients infected with the SARS-CoV-2 virus. These results support the hypothesis of bacterial adaptation to the conditions caused by viral infection.

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SARS-CoV-2病毒感染患者葡萄球菌菌株蛋白谱的变化
金黄色葡萄球菌菌株尤其常从SARS-CoV-2感染患者中分离出来。当前研究的目的是确定SARS-CoV-2病毒感染是否影响金黄色葡萄球菌的蛋白质谱。从博美拉尼亚地区医院收集的40份患者拭子中分离出细菌。使用Microflex LT仪器获得MALDI-TOF质谱。鉴定出29个峰。本文首次描述了峰值(2,430例),并且在从感染SARS-CoV-2病毒的患者分离的病例中是独一无二的。这些结果支持细菌适应由病毒感染引起的条件的假设。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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