{"title":"A Perspective on \"Hypoxia Resistance is an Inherent Phenotype of the Mouse Flexor Digitorum Brevis Skeletal Muscle\".","authors":"Camila Padilha, Ashleigh M Philp","doi":"10.1093/function/zqad024","DOIUrl":null,"url":null,"abstract":"; Hypoxias; r esistance; inher ent; phenotype; mouse Skeletal muscle is reliant on a constant oxygen supply for mov ement, cellular r espiration, and thermogenesis. Heter oge-neous fibre types exist in skeletal muscle as a continuum from slow- to fast-twitch to facilitate specialized function. Type I (oxidati v e fibr es) pr esent a slow-twitc h phenotype , c har acterized by high oxygen capacity and increased fatigue resistance. In contrast, type IIa (fast oxidati v e gl ycol ytic phenotype) and type IIx (fast gl ycol ytic) pr esent faster twitc h speeds and contr","PeriodicalId":73119,"journal":{"name":"Function (Oxford, England)","volume":"4 4","pages":"zqad024"},"PeriodicalIF":3.8000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278979/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Function (Oxford, England)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/function/zqad024","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CELL BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
; Hypoxias; r esistance; inher ent; phenotype; mouse Skeletal muscle is reliant on a constant oxygen supply for mov ement, cellular r espiration, and thermogenesis. Heter oge-neous fibre types exist in skeletal muscle as a continuum from slow- to fast-twitch to facilitate specialized function. Type I (oxidati v e fibr es) pr esent a slow-twitc h phenotype , c har acterized by high oxygen capacity and increased fatigue resistance. In contrast, type IIa (fast oxidati v e gl ycol ytic phenotype) and type IIx (fast gl ycol ytic) pr esent faster twitc h speeds and contr
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