Gingival and alveolar mucosal reactive hyperplastic lesions: a retrospective clinical and histological study of 996 cases.

R-C-P Baesso, R-S Azevedo, B-L Picciani, F-R Pires
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引用次数: 1

Abstract

Background: gingival/alveolar mucosal reactive hyperplastic lesions (GRHL), including fibrous hyperplasia (FH), pyogenic granuloma (PG), peripheral ossifying fibroma (POF) and peripheral giant cell lesion (PGCL), are a common group of oral diseases. The aim of the present study was to access the frequency and distribution of the clinical and histological features of these disorders in a Brazilian population.

Material and methods: all specimens diagnosed as GRHL in three Oral Pathology laboratories were selected for the study. Clinical information was retrieved from the laboratory biopsy forms and hematoxylin and eosin stained histological slides were reviewed for analysis of the histological characteristics.

Results: final sample was composed of 996 specimens, including 463 FH (47%), 280 PG (28%), 183 POF (18%) and 70 PGCL (7%). Females were more affected by FH, PG, and POF, and most cases affected adults with mean ages ranging from 40 to 53 years. FH, PG, and POF were more common in the upper gingiva/alveolar mucosa. Most PG, POF and PGCL were pedunculated, in contrast with FH (p<0.001). PG, FH and POF were mostly red or normal mucosal in color, while PGCL were mostly red/purple (p<0.001). PGCL were larger, followed by POF, FH and PG (p<0.001). Some histological features were characteristically found in some conditions, but they were also encountered in other lesions with variable frequencies.

Conclusions: Oral medicine specialists, oral pathologists and periodontists are usually the professionals in contact with patients presenting GRHL and it is of upmost relevance that they should be familiarized with their clinical and histological profile.

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龈、牙槽粘膜反应性增生性病变:996例临床及组织学回顾性研究。
背景:牙龈/牙槽粘膜反应性增生性病变(GRHL),包括纤维增生(FH)、化脓性肉芽肿(PG)、外周骨化纤维瘤(POF)和外周巨细胞病变(PGCL),是一类常见的口腔疾病。本研究的目的是获取巴西人群中这些疾病的临床和组织学特征的频率和分布。材料和方法:选择三个口腔病理实验室诊断为GRHL的标本进行研究。临床资料从实验室活检表格和苏木精和伊红染色的组织学切片中检索,以分析组织学特征。结果:最终标本共996份,其中FH 463份(47%),PG 280份(28%),POF 183份(18%),PGCL 70份(7%)。女性以FH、PG和POF多见,且多为平均年龄40 ~ 53岁的成年人。FH、PG、POF多见于上龈/牙槽黏膜。结论:口腔医学专家、口腔病理学家和牙周病专家通常是与GRHL患者接触的专业人员,他们应该熟悉他们的临床和组织学特征。
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来源期刊
CiteScore
4.50
自引率
0.00%
发文量
52
期刊介绍: 1. Oral Medicine and Pathology: Clinicopathological as well as medical or surgical management aspects of diseases affecting oral mucosa, salivary glands, maxillary bones, as well as orofacial neurological disorders, and systemic conditions with an impact on the oral cavity. 2. Oral Surgery: Surgical management aspects of diseases affecting oral mucosa, salivary glands, maxillary bones, teeth, implants, oral surgical procedures. Surgical management of diseases affecting head and neck areas. 3. Medically compromised patients in Dentistry: Articles discussing medical problems in Odontology will also be included, with a special focus on the clinico-odontological management of medically compromised patients, and considerations regarding high-risk or disabled patients. 4. Implantology 5. Periodontology
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