{"title":"MSH-5: malignant knee tumors timely detection index.","authors":"Gustavo Rivera-Saldívar, Rubén Torres-González, Alejandra Cario-Méndez, Romeo Técualt-Gómez, Rubén A Amaya-Zepeda, Armando Alcántara-Corona, Silvestre Fuentes-Figueroa","doi":"10.24875/CIRU.21000907","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Bone neoplasms are usually misdiagnosed causing a delay in their treatment. Bone neoplasms are usually confused with tendinitis, 31% of the cases corresponds to osteosarcomas and in 21% to Ewing's sarcomas.</p><p><strong>Objective: </strong>To create a clinical-radiographic instrument of high diagnostic suspicion of knee bone neoplasms to prevent a delay in diagnosis.</p><p><strong>Method: </strong>A clinimetric study (sensitivity, consistency and validity) was performed in the bone tumor service, Hospital de Ortopedia de la Unidad Médica de Alta Especialidad Dr. Victorio de la Fuente Narváez, Instituto Mexicano del Seguro Social, in México City.</p><p><strong>Results: </strong>Characteristics of 153 patients were collected. For the sensitivity phase, 3 domains (signs, symptoms, and radiology) and 12 items were included. Consistency was evaluated with ICC (0.944), 95%CI (0.865-0.977), p < 0.001 and a-Cronbach (0.863). Index obtained a sensitivity of 0.80 and a specificity of 0.882 were obtained. The positive predictive value of the test was 66.6% and the negative predictive value was 93.75%. The positive likelihood ratio was 6.8 and the negative likelihood ratio was 0.2. Validity was evaluated using r-Pearson (0.894; p < 0.001).</p><p><strong>Conclusions: </strong>A high suspicion clinical-radiographic index was designed to detect malignant knee tumors with adequate sensitivity, specificity, appearance, content, criteria, and construct validity.</p>","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 2","pages":"146-152"},"PeriodicalIF":0.5000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cirugia Y Cirujanos","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.24875/CIRU.21000907","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"SURGERY","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Bone neoplasms are usually misdiagnosed causing a delay in their treatment. Bone neoplasms are usually confused with tendinitis, 31% of the cases corresponds to osteosarcomas and in 21% to Ewing's sarcomas.
Objective: To create a clinical-radiographic instrument of high diagnostic suspicion of knee bone neoplasms to prevent a delay in diagnosis.
Method: A clinimetric study (sensitivity, consistency and validity) was performed in the bone tumor service, Hospital de Ortopedia de la Unidad Médica de Alta Especialidad Dr. Victorio de la Fuente Narváez, Instituto Mexicano del Seguro Social, in México City.
Results: Characteristics of 153 patients were collected. For the sensitivity phase, 3 domains (signs, symptoms, and radiology) and 12 items were included. Consistency was evaluated with ICC (0.944), 95%CI (0.865-0.977), p < 0.001 and a-Cronbach (0.863). Index obtained a sensitivity of 0.80 and a specificity of 0.882 were obtained. The positive predictive value of the test was 66.6% and the negative predictive value was 93.75%. The positive likelihood ratio was 6.8 and the negative likelihood ratio was 0.2. Validity was evaluated using r-Pearson (0.894; p < 0.001).
Conclusions: A high suspicion clinical-radiographic index was designed to detect malignant knee tumors with adequate sensitivity, specificity, appearance, content, criteria, and construct validity.
背景:骨肿瘤通常被误诊,导致治疗延误。骨肿瘤通常与肌腱炎混淆,31%的病例对应骨肉瘤,21%对应尤文氏肉瘤。目的:研制一种膝关节骨肿瘤高诊断怀疑度的临床x线仪,防止诊断延误。方法:采用临床计量学研究(敏感性、一致性和效度),在姆萨梅斯科市姆萨梅斯卡阿尔塔联合骨科医院(Hospital de la unidia de Alta especita)的vicio de la Fuente博士Narváez、墨西哥社会医学研究所(Instituto Mexicano del Seguro Social)骨肿瘤科进行研究。结果:收集了153例患者的特征。敏感期包括3个领域(体征、症状和放射学)和12个项目。一致性评价采用ICC(0.944)、95%CI(0.865 ~ 0.977)、p < 0.001和a-Cronbach(0.863)。该指标敏感性为0.80,特异性为0.882。阳性预测值为66.6%,阴性预测值为93.75%。阳性似然比为6.8,阴性似然比为0.2。效度采用r-Pearson (0.894;P < 0.001)。结论:设计了一种高怀疑度的临床放射学指标,以检测膝关节恶性肿瘤,具有足够的敏感性、特异性、外观、内容、标准和结构效度。
期刊介绍:
Cirugía y Cirujanoses exponente del desarrollo académico, científico, médico, quirúrgico y tecnológico en materia de salud en México y en el ámbito internacional. Es una revista bimestral, open access, revisada por pares, que publica en español y en inglés (traducido sin coste para los autores) artículos científicos originales, casos clínicos, artículos de revisión de interés general y cartas al editor. Los artículos se seleccionan y publican siguiendo un riguroso análisis, de acuerdo con los estándares internacionalmente aceptados. Sus espacios están abiertos a los académicos, así como a todo miembro de la comunidad médica que manifieste interés por utilizar este foro para publicar sus trabajos.