Immune-enhancing Effects of Chitosan-fermented Feed Additive on Broiler Chickens and Subsequent Protection Conferred against Experimental Infection with Salmonella Gallinarum.

IF 1.8 4区 农林科学 Q2 AGRICULTURE, DAIRY & ANIMAL SCIENCE Journal of Poultry Science Pub Date : 2023-01-01 DOI:10.2141/jpsa.2023016
Bo Mi Park, Jina Lee, Young Kyu Park, Young Cheol Yang, Bock Gie Jung, Bong Joo Lee
{"title":"Immune-enhancing Effects of Chitosan-fermented Feed Additive on Broiler Chickens and Subsequent Protection Conferred against Experimental Infection with <i>Salmonella</i> Gallinarum.","authors":"Bo Mi Park,&nbsp;Jina Lee,&nbsp;Young Kyu Park,&nbsp;Young Cheol Yang,&nbsp;Bock Gie Jung,&nbsp;Bong Joo Lee","doi":"10.2141/jpsa.2023016","DOIUrl":null,"url":null,"abstract":"<p><p>Benefits chitosan-fermented feed additives (CFFAs) particularly in the regulation of the immune system and antimicrobial activity. Therefore, we investigated the immune-enhancing and bacterial clearance effects of CFFA (fermented by <i>Bacillus licheniformis</i>) on broiler chickens <i>Salmonella</i> Gallinarum challenge. We administered 2% or 4% CFFA evaluated its immune-enhancing effects using several immunological experiments, including examination of lysozyme activity, lymphocyte proliferation, and expression of cytokines. We also evaluated the bacterial clearance effects of CFFA against <i>S.</i> Gallinarum. CFFA administration markedly enhanced lysozyme activity, lymphocyte proliferation, and the expression of interleukin (IL)-2, IL-12, tumor necrosis factor alpha, and interferon gamma in the spleen. In broilers challenged with <i>S.</i> Gallinarum, the clinical signs of <i>S.</i> Gallinarum infection and the number of viable bacterial colonies in the feces and tissues decreased in both CFFA groups. Therefore, CFFAs could be good candidates for feed additive to improve nonspecific immune responses and bacterial clearance.</p>","PeriodicalId":16883,"journal":{"name":"Journal of Poultry Science","volume":null,"pages":null},"PeriodicalIF":1.8000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4c/37/jpsa-60-2023016.PMC10325949.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Poultry Science","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.2141/jpsa.2023016","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"AGRICULTURE, DAIRY & ANIMAL SCIENCE","Score":null,"Total":0}
引用次数: 0

Abstract

Benefits chitosan-fermented feed additives (CFFAs) particularly in the regulation of the immune system and antimicrobial activity. Therefore, we investigated the immune-enhancing and bacterial clearance effects of CFFA (fermented by Bacillus licheniformis) on broiler chickens Salmonella Gallinarum challenge. We administered 2% or 4% CFFA evaluated its immune-enhancing effects using several immunological experiments, including examination of lysozyme activity, lymphocyte proliferation, and expression of cytokines. We also evaluated the bacterial clearance effects of CFFA against S. Gallinarum. CFFA administration markedly enhanced lysozyme activity, lymphocyte proliferation, and the expression of interleukin (IL)-2, IL-12, tumor necrosis factor alpha, and interferon gamma in the spleen. In broilers challenged with S. Gallinarum, the clinical signs of S. Gallinarum infection and the number of viable bacterial colonies in the feces and tissues decreased in both CFFA groups. Therefore, CFFAs could be good candidates for feed additive to improve nonspecific immune responses and bacterial clearance.

Abstract Image

Abstract Image

Abstract Image

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
壳聚糖发酵饲料添加剂对肉鸡免疫增强作用及对鸡沙门氏菌实验感染的保护作用
壳聚糖发酵饲料添加剂(CFFAs)的益处,特别是在调节免疫系统和抗菌活性方面。因此,我们研究了由地衣芽孢杆菌发酵的CFFA对肉鸡沙门氏菌攻击的免疫增强和细菌清除作用。我们给药2%或4%的CFFA,通过几个免疫学实验评估其免疫增强作用,包括溶菌酶活性、淋巴细胞增殖和细胞因子表达的检测。我们还评估了CFFA对鸡链球菌的细菌清除作用。CFFA显著提高脾脏溶菌酶活性、淋巴细胞增殖以及白细胞介素(IL)-2、IL-12、肿瘤坏死因子α和干扰素γ的表达。在感染鸡链球菌的肉鸡中,两组CFFA均降低了鸡链球菌感染的临床症状以及粪便和组织中活菌落的数量。因此,CFFAs可作为提高非特异性免疫反应和细菌清除率的饲料添加剂。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Journal of Poultry Science
Journal of Poultry Science AGRICULTURE, DAIRY & ANIMAL SCIENCE-
CiteScore
2.80
自引率
13.30%
发文量
26
审稿时长
12 months
期刊介绍: The Journal of Poultry Science will publish original reports and reviews which either make an original contribution to fundamental science or are of obvious application to the industry. Subjects which are covered include: breeding and genetics, nutrition and feeds, physiology, reproduction, immunology, behavior, environmental science, management and housing welfare, processing and products, and health in poultry. Submission of original articles to the Journal is open to all poultry researchers. The review articles are invited papers written by international outstanding researchers. Articles will be published in English, American style.
期刊最新文献
Effect of a Mixed Fermented Loquat Leaf Tea By-Product on the Growth Performance and Meat Quality of Tsushima-Jidori Crossbred Chicken. Erratum: Egg Quality, Sensory Attributes, and Protein Metabolites of Laying Hens Fed Whole Flaxseed, Fish Oil, and Different Sources of Trace Elements. Association between Temperament and Stress-related Gene Expression in Day-old Chickens. Egg Quality, Sensory Attributes, and Protein Metabolites of Laying Hens Fed Whole Flaxseed, Fish Oil, and Different Sources of Trace Elements. Formation of the Pecking Order during Small-Scale Floor Feeding in Helmeted Guinea Fowl (Numida meleagris).
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1