Epidemiology of nosocomial Staphylococcus epidermidis and Acinetobacter baumannii infections in a neonatal intensive care unit.

IF 1.3 Q4 MICROBIOLOGY Iranian Journal of Microbiology Pub Date : 2023-06-01 DOI:10.18502/ijm.v15i3.12895

Fatemeh Nayeri, Hosein Dalili, Mamak Shariat, Nahid Farrokhzad, Kosar Abouhamzeh, Leyla Sahebi

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Abstract

Background and objectives: This study aimed to investigate epidemiology of Staphylococcus epidermidis (S. epidermidis) and Acinetobacter baumannii (A. baumannii) infections in neonatal intensive care unit (NICU) in a period of 8 years.

Materials and methods: This retrospective cohort study was conducted on 46 cases of nosocomial infection by S. epidermidis, and 44 neonates with A. baumannii in NICU of Valiasr hospital, Iran.

Results: The trend of A. baumannii and S. epidermidis infection were as follows: 1 and 7 in 2014, 11 and 7 in 2015, 20 and 11 in 2016, 1 and 4 in 2017, 4 and 6 in 2018, 4 and 4 in 2019, 0 and 1 in 2020, and 3 and 6 in 2021-March 2022 respectively. Mortality proportion (%) in neonates with S. epidermidis and A. baumannii infection was at 8.3 and 32.1, respectively. There was a strong positive correlation between number of infected neonates in month and average of prescribed antibiotics before incidence of infection in every baby in that month. Fluconazole prescription before incidence of infection were associated with the A. baumannii infection in month too. Amikacin prescription had adjusted correlation on increasing of A. baumannii and S. epidermidis infection in month.

Conclusion: It seems reducing of hospitalization duration and medication prescriptions management plays an important role in reducing of nosocomial infections.

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新生儿重症监护室院内表皮葡萄球菌和鲍曼不动杆菌感染的流行病学。

背景与目的:本研究旨在调查8年新生儿重症监护病房(NICU)表皮葡萄球菌(S. epidermidis)和鲍曼不动杆菌(a . baumannii)感染的流行病学。材料与方法:对伊朗Valiasr医院NICU收治的46例表皮葡萄球菌院内感染和44例鲍曼不雅杆菌新生儿进行回顾性队列研究。结果:鲍曼不动杆菌和表皮葡萄球菌感染趋势分别为:2014年1和7,2015年11和7,2016年20和11,2017年1和4,2018年4和6,2019年4和4,2020年0和1,2021- 2022年3月3和6。感染表皮葡萄球菌和鲍曼不动杆菌的新生儿死亡率分别为8.3和32.1。该月感染新生儿数与该月每个婴儿感染发生率前平均处方抗生素用量呈正相关。氟康唑处方前感染发生率与当月鲍曼不动杆菌感染发生率也有相关性。阿米卡星处方与鲍曼不动杆菌和表皮葡萄球菌感染的增加呈正相关。结论:缩短住院时间和药物处方管理对减少院内感染具有重要作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Iranian Journal of Microbiology MICROBIOLOGY-

CiteScore

2.40

自引率

7.10%

发文量

审稿时长

12 weeks

期刊介绍： The Iranian Journal of Microbiology (IJM) is an international, multi-disciplinary, peer-reviewed journal that provides rapid publication of the most advanced scientific research in the areas of basic and applied research on bacteria and other micro-organisms, including bacteria, viruses, yeasts, fungi, microalgae, and protozoa concerning the development of tools for diagnosis and disease control, epidemiology, antimicrobial agents, clinical microbiology, immunology, Genetics, Genomics and Molecular Biology. Contributions may be in the form of original research papers, review articles, short communications, case reports, technical reports, and letters to the Editor. Research findings must be novel and the original data must be available for review by the Editors, if necessary. Studies that are preliminary, of weak originality or merely descriptive as well as negative results are not appropriate for the journal. Papers considered for publication must be unpublished work (except in an abstract form) that is not under consideration for publication anywhere else, and all co-authors should have agreed to the submission. Manuscripts should be written in English.