{"title":"Detection of Cerebrovascular Diseases using Novel Discrete Component Wavelet Cosine Transform.","authors":"Bandana Pal, Shruti Jain","doi":"10.2174/1573409919666221209151534","DOIUrl":null,"url":null,"abstract":"<p><strong>Aims: </strong>Detecting and classifying a brain tumor amid a sole image can be problematic for doctors, although improvements can be made with medical image fusions.</p><p><strong>Background: </strong>A brain tumor develops in the tissues surrounding the brain or the skull and has a major impact on human life. Primary tumors begin within the brain, whereas secondary tumors, identified as brain metastasis tumors, are generated outside the brain.</p><p><strong>Objective: </strong>This paper proposes hybrid fusion techniques to fuse multi-modal images. The evaluations are based on performance metrics, and the results are compared with conventional ones.</p><p><strong>Methods: </strong>In this paper, pre-processing is done considering enhancement methods like Binarization, Contrast Stretching, Median Filter, & Contrast Limited Adaptive Histogram Equalization (CLAHE). Authors have proposed three techniques, PCA-DWT, DCT-PCA, and Discrete ComponentWaveletCosine Transform (DCWCT), which were used to fuse CT-MR images of brain tumors.</p><p><strong>Results: </strong>The different features were evaluated from the fused images, which were classified using various machine learning approaches. Maximum accuracy of 97.9% and 93.5% is obtained using DCWCT for Support Vector Machine (SVM) and k Nearest Neighbor (kNN), respectively, considering the combination of both feature's shape & Grey Level Difference Statistics. The model is validated using another online dataset.</p><p><strong>Conclusion: </strong>It has been observed that the classification accuracy for detecting cerebrovascular disease is better after employing the proposed image fusion technique.</p>","PeriodicalId":10886,"journal":{"name":"Current computer-aided drug design","volume":"19 2","pages":"137-149"},"PeriodicalIF":1.5000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current computer-aided drug design","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2174/1573409919666221209151534","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
引用次数: 0
Abstract
Aims: Detecting and classifying a brain tumor amid a sole image can be problematic for doctors, although improvements can be made with medical image fusions.
Background: A brain tumor develops in the tissues surrounding the brain or the skull and has a major impact on human life. Primary tumors begin within the brain, whereas secondary tumors, identified as brain metastasis tumors, are generated outside the brain.
Objective: This paper proposes hybrid fusion techniques to fuse multi-modal images. The evaluations are based on performance metrics, and the results are compared with conventional ones.
Methods: In this paper, pre-processing is done considering enhancement methods like Binarization, Contrast Stretching, Median Filter, & Contrast Limited Adaptive Histogram Equalization (CLAHE). Authors have proposed three techniques, PCA-DWT, DCT-PCA, and Discrete ComponentWaveletCosine Transform (DCWCT), which were used to fuse CT-MR images of brain tumors.
Results: The different features were evaluated from the fused images, which were classified using various machine learning approaches. Maximum accuracy of 97.9% and 93.5% is obtained using DCWCT for Support Vector Machine (SVM) and k Nearest Neighbor (kNN), respectively, considering the combination of both feature's shape & Grey Level Difference Statistics. The model is validated using another online dataset.
Conclusion: It has been observed that the classification accuracy for detecting cerebrovascular disease is better after employing the proposed image fusion technique.
期刊介绍:
Aims & Scope
Current Computer-Aided Drug Design aims to publish all the latest developments in drug design based on computational techniques. The field of computer-aided drug design has had extensive impact in the area of drug design.
Current Computer-Aided Drug Design is an essential journal for all medicinal chemists who wish to be kept informed and up-to-date with all the latest and important developments in computer-aided methodologies and their applications in drug discovery. Each issue contains a series of timely, in-depth reviews, original research articles and letter articles written by leaders in the field, covering a range of computational techniques for drug design, screening, ADME studies, theoretical chemistry; computational chemistry; computer and molecular graphics; molecular modeling; protein engineering; drug design; expert systems; general structure-property relationships; molecular dynamics; chemical database development and usage etc., providing excellent rationales for drug development.